The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis.

p38 mitogen-activated protein kinase (MAPK) is thought to play a central role in acute and chronic inflammatory responses. Whether p38MAPK plays a pathogenic role in crescentic GN (GN) and which of its four isoforms is preferentially involved in kidney inflammation is not definitely known. We thus e...

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Bibliographic Details
Main Authors: Ralf Müller, Christoph Daniel, Christian Hugo, Kerstin Amann, Dirk Mielenz, Karlhans Endlich, Tobias Braun, Betty van der Veen, Peter Heeringa, Georg Schett, Jochen Zwerina
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/55b4f2a8753b4fe3bd95f7f934f33169
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