Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy

Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy

Abstract Background Elevated mammographic breast density is a strong breast cancer risk factor with poorly understood etiology. Increased deposition of collagen, one of the main fibrous proteins present in breast stroma, has been associated with increased mammographic density. Collagen fiber archite...

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Main Authors: Clara Bodelon, Maeve Mullooly, Ruth M. Pfeiffer, Shaoqi Fan, Mustapha Abubakar, Petra Lenz, Pamela M. Vacek, Donald L. Weaver, Sally D. Herschorn, Jason M. Johnson, Brian L. Sprague, Stephen Hewitt, John Shepherd, Serghei Malkov, Patricia J. Keely, Kevin W. Eliceiri, Mark E. Sherman, Matthew W. Conklin, Gretchen L. Gierach
Format: article
Language:EN
Published: BMC 2021
Subjects:
Collagen fibers
Mammographic density
Breast pathology
Second harmonic generation imaging
Breast diseases
Breast neoplasms
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/55b709f4e4e248f1bf8d0e98540e2bf9
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https://doaj.org/article/55b709f4e4e248f1bf8d0e98540e2bf9

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