Near-infrared uncaging or photosensitizing dictated by oxygen tension
The generation of reactive oxygen species (ROS) in photodynamic cancer treatments is limited by low intraturmoural oxygen availability. Here the authors show that irradiation of a silicon phthalocyanine leads to uncaging of a biologically active molecule or to ROS formation in an oxygen-dependent ma...
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Nature Portfolio
2016
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oai:doaj.org-article:55b7fcf9660b42abb4b9611ecddf914c2021-12-02T15:34:54ZNear-infrared uncaging or photosensitizing dictated by oxygen tension10.1038/ncomms133782041-1723https://doaj.org/article/55b7fcf9660b42abb4b9611ecddf914c2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13378https://doaj.org/toc/2041-1723The generation of reactive oxygen species (ROS) in photodynamic cancer treatments is limited by low intraturmoural oxygen availability. Here the authors show that irradiation of a silicon phthalocyanine leads to uncaging of a biologically active molecule or to ROS formation in an oxygen-dependent manner.Erin D. AndersonAlexander P. GorkaMartin J. SchnermannNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Erin D. Anderson Alexander P. Gorka Martin J. Schnermann Near-infrared uncaging or photosensitizing dictated by oxygen tension |
description |
The generation of reactive oxygen species (ROS) in photodynamic cancer treatments is limited by low intraturmoural oxygen availability. Here the authors show that irradiation of a silicon phthalocyanine leads to uncaging of a biologically active molecule or to ROS formation in an oxygen-dependent manner. |
format |
article |
author |
Erin D. Anderson Alexander P. Gorka Martin J. Schnermann |
author_facet |
Erin D. Anderson Alexander P. Gorka Martin J. Schnermann |
author_sort |
Erin D. Anderson |
title |
Near-infrared uncaging or photosensitizing dictated by oxygen tension |
title_short |
Near-infrared uncaging or photosensitizing dictated by oxygen tension |
title_full |
Near-infrared uncaging or photosensitizing dictated by oxygen tension |
title_fullStr |
Near-infrared uncaging or photosensitizing dictated by oxygen tension |
title_full_unstemmed |
Near-infrared uncaging or photosensitizing dictated by oxygen tension |
title_sort |
near-infrared uncaging or photosensitizing dictated by oxygen tension |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/55b7fcf9660b42abb4b9611ecddf914c |
work_keys_str_mv |
AT erindanderson nearinfrareduncagingorphotosensitizingdictatedbyoxygentension AT alexanderpgorka nearinfrareduncagingorphotosensitizingdictatedbyoxygentension AT martinjschnermann nearinfrareduncagingorphotosensitizingdictatedbyoxygentension |
_version_ |
1718386719125929984 |