Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits

Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis.

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Autores principales: Luis E. Contreras-Llano, Conary Meyer, Yao Liu, Mridul Sarker, Sierin Lim, Marjorie L. Longo, Cheemeng Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/55bac5fd16a4402198c0d94a339bb781
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spelling oai:doaj.org-article:55bac5fd16a4402198c0d94a339bb7812021-12-02T17:40:35ZHolistic engineering of cell-free systems through proteome-reprogramming synthetic circuits10.1038/s41467-020-16900-72041-1723https://doaj.org/article/55bac5fd16a4402198c0d94a339bb7812020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16900-7https://doaj.org/toc/2041-1723Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis.Luis E. Contreras-LlanoConary MeyerYao LiuMridul SarkerSierin LimMarjorie L. LongoCheemeng TanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Luis E. Contreras-Llano
Conary Meyer
Yao Liu
Mridul Sarker
Sierin Lim
Marjorie L. Longo
Cheemeng Tan
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
description Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis.
format article
author Luis E. Contreras-Llano
Conary Meyer
Yao Liu
Mridul Sarker
Sierin Lim
Marjorie L. Longo
Cheemeng Tan
author_facet Luis E. Contreras-Llano
Conary Meyer
Yao Liu
Mridul Sarker
Sierin Lim
Marjorie L. Longo
Cheemeng Tan
author_sort Luis E. Contreras-Llano
title Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
title_short Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
title_full Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
title_fullStr Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
title_full_unstemmed Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
title_sort holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/55bac5fd16a4402198c0d94a339bb781
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