Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis.
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Nature Portfolio
2020
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oai:doaj.org-article:55bac5fd16a4402198c0d94a339bb7812021-12-02T17:40:35ZHolistic engineering of cell-free systems through proteome-reprogramming synthetic circuits10.1038/s41467-020-16900-72041-1723https://doaj.org/article/55bac5fd16a4402198c0d94a339bb7812020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16900-7https://doaj.org/toc/2041-1723Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis.Luis E. Contreras-LlanoConary MeyerYao LiuMridul SarkerSierin LimMarjorie L. LongoCheemeng TanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Luis E. Contreras-Llano Conary Meyer Yao Liu Mridul Sarker Sierin Lim Marjorie L. Longo Cheemeng Tan Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
description |
Synthetic biological modules can be used to reprogram host proteomes, which in turn enhance the function of the synthetic modules. The authors use this holistic synthetic biology approach to engineer a more favorable environment for cell-free protein synthesis. |
format |
article |
author |
Luis E. Contreras-Llano Conary Meyer Yao Liu Mridul Sarker Sierin Lim Marjorie L. Longo Cheemeng Tan |
author_facet |
Luis E. Contreras-Llano Conary Meyer Yao Liu Mridul Sarker Sierin Lim Marjorie L. Longo Cheemeng Tan |
author_sort |
Luis E. Contreras-Llano |
title |
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
title_short |
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
title_full |
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
title_fullStr |
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
title_full_unstemmed |
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
title_sort |
holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/55bac5fd16a4402198c0d94a339bb781 |
work_keys_str_mv |
AT luisecontrerasllano holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT conarymeyer holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT yaoliu holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT mridulsarker holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT sierinlim holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT marjoriellongo holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits AT cheemengtan holisticengineeringofcellfreesystemsthroughproteomereprogrammingsyntheticcircuits |
_version_ |
1718379763606749184 |