Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity

Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in m...

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Autores principales:	Dwi Andriani, SYAMSULINA REVIANTI, WIDYASRI PRANANINGRUM
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	acanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compound Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/55bb0914fcba4cc2b4d4bed4a783b8b0
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spelling	oai:doaj.org-article:55bb0914fcba4cc2b4d4bed4a783b8b02021-11-22T00:40:46ZIdentification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity1412-033X2085-472210.13057/biodiv/d210625https://doaj.org/article/55bb0914fcba4cc2b4d4bed4a783b8b02020-05-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5649https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in mangroves along the east coast of Surabaya. It can be used as an indicator of environmental pollution and damage in mangrove ecosystems. Studies have reported that A. ilicifolius has antimicrobial, antifungal, antiviral, anti-inflammatory, analgesic, antioxidant, anticancer, antileishmanial, and hepatoprotective activity due to the chemical compounds in the plant. This study aimed to determine the phytochemical compounds in methanolic extracts of A. ilicifolius and their antifungal and antioxidant activity. The study involved laboratory experiments with a post-test only control group design. Antifungal activity against Candida albicans biofilm was determined using microtiter plates. Antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Phytochemical screening used colorimetric methods. Methanolic extracts of A. ilicifolius at 16% and 20% concentration had the same inhibitory effect as nystatin against C. albicans (about 70% inhibition of biofilm). Chemical compounds identified in the extract included flavonoids, alkaloids, glycosides, polyphenols, tannins, and steroids. Methanolic extracts of A. ilicifolius have strong antioxidant and antifungal activity, and the plant’s phytochemical compounds are potential candidates for antifungal therapy.Dwi AndrianiSYAMSULINA REVIANTIWIDYASRI PRANANINGRUMMBI & UNS Soloarticleacanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compoundBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	acanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compound Biology (General) QH301-705.5
spellingShingle	acanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compound Biology (General) QH301-705.5 Dwi Andriani SYAMSULINA REVIANTI WIDYASRI PRANANINGRUM Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
description	Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in mangroves along the east coast of Surabaya. It can be used as an indicator of environmental pollution and damage in mangrove ecosystems. Studies have reported that A. ilicifolius has antimicrobial, antifungal, antiviral, anti-inflammatory, analgesic, antioxidant, anticancer, antileishmanial, and hepatoprotective activity due to the chemical compounds in the plant. This study aimed to determine the phytochemical compounds in methanolic extracts of A. ilicifolius and their antifungal and antioxidant activity. The study involved laboratory experiments with a post-test only control group design. Antifungal activity against Candida albicans biofilm was determined using microtiter plates. Antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Phytochemical screening used colorimetric methods. Methanolic extracts of A. ilicifolius at 16% and 20% concentration had the same inhibitory effect as nystatin against C. albicans (about 70% inhibition of biofilm). Chemical compounds identified in the extract included flavonoids, alkaloids, glycosides, polyphenols, tannins, and steroids. Methanolic extracts of A. ilicifolius have strong antioxidant and antifungal activity, and the plant’s phytochemical compounds are potential candidates for antifungal therapy.
format	article
author	Dwi Andriani SYAMSULINA REVIANTI WIDYASRI PRANANINGRUM
author_facet	Dwi Andriani SYAMSULINA REVIANTI WIDYASRI PRANANINGRUM
author_sort	Dwi Andriani
title	Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_short	Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_full	Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_fullStr	Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_full_unstemmed	Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_sort	identification of compounds isolated from a methanolic extract of acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/55bb0914fcba4cc2b4d4bed4a783b8b0
work_keys_str_mv	AT dwiandriani identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity AT syamsulinarevianti identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity AT widyasriprananingrum identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity
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Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity

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