Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity

Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in m...

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Autores principales: Dwi Andriani, SYAMSULINA REVIANTI, WIDYASRI PRANANINGRUM
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Publicado: MBI & UNS Solo 2020
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spelling oai:doaj.org-article:55bb0914fcba4cc2b4d4bed4a783b8b02021-11-22T00:40:46ZIdentification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity1412-033X2085-472210.13057/biodiv/d210625https://doaj.org/article/55bb0914fcba4cc2b4d4bed4a783b8b02020-05-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5649https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in mangroves along the east coast of Surabaya. It can be used as an indicator of environmental pollution and damage in mangrove ecosystems. Studies have reported that A. ilicifolius has antimicrobial, antifungal, antiviral, anti-inflammatory, analgesic, antioxidant, anticancer, antileishmanial, and hepatoprotective activity due to the chemical compounds in the plant. This study aimed to determine the phytochemical compounds in methanolic extracts of A. ilicifolius and their antifungal and antioxidant activity. The study involved laboratory experiments with a post-test only control group design. Antifungal activity against Candida albicans biofilm was determined using microtiter plates. Antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Phytochemical screening used colorimetric methods. Methanolic extracts of A. ilicifolius at 16% and 20% concentration had the same inhibitory effect as nystatin against C. albicans (about 70% inhibition of biofilm). Chemical compounds identified in the extract included flavonoids, alkaloids, glycosides, polyphenols, tannins, and steroids. Methanolic extracts of A. ilicifolius have strong antioxidant and antifungal activity, and the plant’s phytochemical compounds are potential candidates for antifungal therapy.Dwi AndrianiSYAMSULINA REVIANTIWIDYASRI PRANANINGRUMMBI & UNS Soloarticleacanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compoundBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 6 (2020)
institution DOAJ
collection DOAJ
language EN
topic acanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compound
Biology (General)
QH301-705.5
spellingShingle acanthus ilicifolius, candida albicans biofilm, antioxidant, phytochemical compound
Biology (General)
QH301-705.5
Dwi Andriani
SYAMSULINA REVIANTI
WIDYASRI PRANANINGRUM
Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
description Abstract. Andriani D, Revianti S, Prananingrum W. 2020. Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity. Biodiversitas 21: 2521-2525. Acanthus ilicifolius L. (Acanthaceae) is commonly found in mangroves along the east coast of Surabaya. It can be used as an indicator of environmental pollution and damage in mangrove ecosystems. Studies have reported that A. ilicifolius has antimicrobial, antifungal, antiviral, anti-inflammatory, analgesic, antioxidant, anticancer, antileishmanial, and hepatoprotective activity due to the chemical compounds in the plant. This study aimed to determine the phytochemical compounds in methanolic extracts of A. ilicifolius and their antifungal and antioxidant activity. The study involved laboratory experiments with a post-test only control group design. Antifungal activity against Candida albicans biofilm was determined using microtiter plates. Antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Phytochemical screening used colorimetric methods. Methanolic extracts of A. ilicifolius at 16% and 20% concentration had the same inhibitory effect as nystatin against C. albicans (about 70% inhibition of biofilm). Chemical compounds identified in the extract included flavonoids, alkaloids, glycosides, polyphenols, tannins, and steroids. Methanolic extracts of A. ilicifolius have strong antioxidant and antifungal activity, and the plant’s phytochemical compounds are potential candidates for antifungal therapy.
format article
author Dwi Andriani
SYAMSULINA REVIANTI
WIDYASRI PRANANINGRUM
author_facet Dwi Andriani
SYAMSULINA REVIANTI
WIDYASRI PRANANINGRUM
author_sort Dwi Andriani
title Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_short Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_full Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_fullStr Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_full_unstemmed Identification of compounds isolated from a methanolic extract of Acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
title_sort identification of compounds isolated from a methanolic extract of acanthus ilicifolius leaves and evaluation of their antifungal and antioxidant activity
publisher MBI & UNS Solo
publishDate 2020
url https://doaj.org/article/55bb0914fcba4cc2b4d4bed4a783b8b0
work_keys_str_mv AT dwiandriani identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity
AT syamsulinarevianti identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity
AT widyasriprananingrum identificationofcompoundsisolatedfromamethanolicextractofacanthusilicifoliusleavesandevaluationoftheirantifungalandantioxidantactivity
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