SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY

Objective: To determine the frequency of spontaneous bacterial peritonitis in asymptomatic cirrhotic patients with ascites. Study Design: Cross-sectional study. Place and Duration of Study: Medical outpatient department, Medical unit III, Ward-7, JPMC, Karachi, from Feb 2018 to Aug 2018. Me...

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Autores principales: Asif Aziz, Sarwat Ashraf, Mir Tahir Hussain Talpur, Nasrullah Aamer, Sagheer Ahmed Solangi, Khalil Ullah Shabir, Moiz Ahmed, Kiran Abbas
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Publicado: Army Medical College Rawalpindi 2020
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Acceso en línea:https://doaj.org/article/55beb51c50b94921885b397707b83a06
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spelling oai:doaj.org-article:55beb51c50b94921885b397707b83a062021-12-02T17:20:37ZSPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY0030-96482411-8842https://doaj.org/article/55beb51c50b94921885b397707b83a062020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5574https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency of spontaneous bacterial peritonitis in asymptomatic cirrhotic patients with ascites. Study Design: Cross-sectional study. Place and Duration of Study: Medical outpatient department, Medical unit III, Ward-7, JPMC, Karachi, from Feb 2018 to Aug 2018. Methodology: All patients between the age of 18 to 60 years and presenting with confirmed ascites due to liver cirrhosis were included. Those with ascites due to other causes were excluded from the study. After obtaining consent, diagnostic ascitic paracentesis was done and sent to the laboratory for evaluation. Results: A total of 130 patients were enrolled in the study. The mean age of ascites patients was 46.94 ± 7.67 years. There were 73 (56.2%) male while 57 (43.8%) were female. Spontaneous bacterial peritonitis was detected among 38 (29.2%) patients. Among these, 15 patients (11.5%) had positive culture of spontaneous bacterial peritonitis and detected organisms like E.coli (5.4%), Klebsiella (3.1%), Pneumococcus (2.3%) & Streptococcus viridians (0.8%). Frequency of spontaneous bacterial peritonitis increased with increasing age. Male gender was more affected of spontaneous bacterial peritonitis. Lower the weight increasing duration of ascites were associated with higher incidence of spontaneous bacterial peritonitis (p-value = 0.001 and 0.311 respectively). Conclusion: Spontaneous bacterial peritonitis was detected among one-third of the patients suffering from cirrhosis, making it a grave complication that requires prompt treatment.Asif AzizSarwat AshrafMir Tahir Hussain TalpurNasrullah AamerSagheer Ahmed SolangiKhalil Ullah ShabirMoiz AhmedKiran AbbasArmy Medical College Rawalpindiarticleascitescirrhosisspontaneous bacterial peritonitisMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1408-1412 (2020)
institution DOAJ
collection DOAJ
language EN
topic ascites
cirrhosis
spontaneous bacterial peritonitis
Medicine
R
Medicine (General)
R5-920
spellingShingle ascites
cirrhosis
spontaneous bacterial peritonitis
Medicine
R
Medicine (General)
R5-920
Asif Aziz
Sarwat Ashraf
Mir Tahir Hussain Talpur
Nasrullah Aamer
Sagheer Ahmed Solangi
Khalil Ullah Shabir
Moiz Ahmed
Kiran Abbas
SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
description Objective: To determine the frequency of spontaneous bacterial peritonitis in asymptomatic cirrhotic patients with ascites. Study Design: Cross-sectional study. Place and Duration of Study: Medical outpatient department, Medical unit III, Ward-7, JPMC, Karachi, from Feb 2018 to Aug 2018. Methodology: All patients between the age of 18 to 60 years and presenting with confirmed ascites due to liver cirrhosis were included. Those with ascites due to other causes were excluded from the study. After obtaining consent, diagnostic ascitic paracentesis was done and sent to the laboratory for evaluation. Results: A total of 130 patients were enrolled in the study. The mean age of ascites patients was 46.94 ± 7.67 years. There were 73 (56.2%) male while 57 (43.8%) were female. Spontaneous bacterial peritonitis was detected among 38 (29.2%) patients. Among these, 15 patients (11.5%) had positive culture of spontaneous bacterial peritonitis and detected organisms like E.coli (5.4%), Klebsiella (3.1%), Pneumococcus (2.3%) & Streptococcus viridians (0.8%). Frequency of spontaneous bacterial peritonitis increased with increasing age. Male gender was more affected of spontaneous bacterial peritonitis. Lower the weight increasing duration of ascites were associated with higher incidence of spontaneous bacterial peritonitis (p-value = 0.001 and 0.311 respectively). Conclusion: Spontaneous bacterial peritonitis was detected among one-third of the patients suffering from cirrhosis, making it a grave complication that requires prompt treatment.
format article
author Asif Aziz
Sarwat Ashraf
Mir Tahir Hussain Talpur
Nasrullah Aamer
Sagheer Ahmed Solangi
Khalil Ullah Shabir
Moiz Ahmed
Kiran Abbas
author_facet Asif Aziz
Sarwat Ashraf
Mir Tahir Hussain Talpur
Nasrullah Aamer
Sagheer Ahmed Solangi
Khalil Ullah Shabir
Moiz Ahmed
Kiran Abbas
author_sort Asif Aziz
title SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
title_short SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
title_full SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
title_fullStr SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
title_full_unstemmed SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
title_sort spontaneous bacterial peritonitis in asymptomatic cirrhotic patients with ascites in a tertiary care hospital: a cross-sectional study
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/55beb51c50b94921885b397707b83a06
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