Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both without a systematic pattern of sign concordance.

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Autores principales:	V. Bansal, M. Mitjans, C. A. P. Burik, R. K. Linnér, A. Okbay, C. A. Rietveld, M. Begemann, S. Bonn, S. Ripke, R. de Vlaming, M. G. Nivard, H. Ehrenreich, P. D. Koellinger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/55c327660abc4980b3af8b9db2eaa44a
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spelling	oai:doaj.org-article:55c327660abc4980b3af8b9db2eaa44a2021-12-02T16:49:32ZGenome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia10.1038/s41467-018-05510-z2041-1723https://doaj.org/article/55c327660abc4980b3af8b9db2eaa44a2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05510-zhttps://doaj.org/toc/2041-1723Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both without a systematic pattern of sign concordance.V. BansalM. MitjansC. A. P. BurikR. K. LinnérA. OkbayC. A. RietveldM. BegemannS. BonnS. RipkeR. de VlamingM. G. NivardH. EhrenreichP. D. KoellingerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q V. Bansal M. Mitjans C. A. P. Burik R. K. Linnér A. Okbay C. A. Rietveld M. Begemann S. Bonn S. Ripke R. de Vlaming M. G. Nivard H. Ehrenreich P. D. Koellinger Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
description	Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both without a systematic pattern of sign concordance.
format	article
author	V. Bansal M. Mitjans C. A. P. Burik R. K. Linnér A. Okbay C. A. Rietveld M. Begemann S. Bonn S. Ripke R. de Vlaming M. G. Nivard H. Ehrenreich P. D. Koellinger
author_facet	V. Bansal M. Mitjans C. A. P. Burik R. K. Linnér A. Okbay C. A. Rietveld M. Begemann S. Bonn S. Ripke R. de Vlaming M. G. Nivard H. Ehrenreich P. D. Koellinger
author_sort	V. Bansal
title	Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
title_short	Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
title_full	Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
title_fullStr	Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
title_full_unstemmed	Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
title_sort	genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/55c327660abc4980b3af8b9db2eaa44a
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Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

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