Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and shape of the endoplasmic reticulum. Here authors use molecular modeling and molecular dynamics simulations to assemble a structural model for the reticulon-homology domain of FAM134B.

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Bibliographic Details
Main Authors: Ramachandra M. Bhaskara, Paolo Grumati, Javier Garcia-Pardo, Sissy Kalayil, Adriana Covarrubias-Pinto, Wenbo Chen, Mikhail Kudryashev, Ivan Dikic, Gerhard Hummer
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/55c989931d3643a28f0d1a7f12a1012b
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