Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish

Nadja Brun et al. characterize the impact of early exposure to polychlorinated biphenyls on neural development and behavior in zebrafish. Their results demonstrate that developmental exposure to these chemicals promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in larval zeb...

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Autores principales:	Nadja R. Brun, Jennifer M. Panlilio, Kun Zhang, Yanbin Zhao, Evgeny Ivashkin, John J. Stegeman, Jared V. Goldstone
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/55cafddc22cc4014b467475ef024b999
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spelling	oai:doaj.org-article:55cafddc22cc4014b467475ef024b9992021-12-02T18:48:42ZDevelopmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish10.1038/s42003-021-02626-92399-3642https://doaj.org/article/55cafddc22cc4014b467475ef024b9992021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02626-9https://doaj.org/toc/2399-3642Nadja Brun et al. characterize the impact of early exposure to polychlorinated biphenyls on neural development and behavior in zebrafish. Their results demonstrate that developmental exposure to these chemicals promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in larval zebrafish, suggesting that these chemicals may also contribute to neurodevelopmental abnormalities in humans.Nadja R. BrunJennifer M. PanlilioKun ZhangYanbin ZhaoEvgeny IvashkinJohn J. StegemanJared V. GoldstoneNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Nadja R. Brun Jennifer M. Panlilio Kun Zhang Yanbin Zhao Evgeny Ivashkin John J. Stegeman Jared V. Goldstone Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
description	Nadja Brun et al. characterize the impact of early exposure to polychlorinated biphenyls on neural development and behavior in zebrafish. Their results demonstrate that developmental exposure to these chemicals promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in larval zebrafish, suggesting that these chemicals may also contribute to neurodevelopmental abnormalities in humans.
format	article
author	Nadja R. Brun Jennifer M. Panlilio Kun Zhang Yanbin Zhao Evgeny Ivashkin John J. Stegeman Jared V. Goldstone
author_facet	Nadja R. Brun Jennifer M. Panlilio Kun Zhang Yanbin Zhao Evgeny Ivashkin John J. Stegeman Jared V. Goldstone
author_sort	Nadja R. Brun
title	Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
title_short	Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
title_full	Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
title_fullStr	Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
title_full_unstemmed	Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish
title_sort	developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and gabaergic signaling in zebrafish
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/55cafddc22cc4014b467475ef024b999
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Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish

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