AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)

At present time, the issue of age-dependence of morphological parameters of the thymus blood vessels in members of various terrestrial vertebrates classes has been poorly studied, due to the lack of comparative morphological approaches. Therefore, the main goal of our work was to specify this kind o...

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Autor principal:	V. Ya. Yurchinskiy
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2018
Materias:	thymus vertebrate animals correlation analysis age-related changes comparative morphology Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/55cc5c3a088d4265a6ab2c55610c3660
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id	oai:doaj.org-article:55cc5c3a088d4265a6ab2c55610c3660
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spelling	oai:doaj.org-article:55cc5c3a088d4265a6ab2c55610c36602021-11-18T08:03:47ZAGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)1563-06252313-741X10.15789/1563-0625-2018-4-571-576https://doaj.org/article/55cc5c3a088d4265a6ab2c55610c36602018-06-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1565https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAt present time, the issue of age-dependence of morphological parameters of the thymus blood vessels in members of various terrestrial vertebrates classes has been poorly studied, due to the lack of comparative morphological approaches. Therefore, the main goal of our work was to specify this kind of dependences. We studied samples of thymus glands from vertebrate animals belonging to four classes: Amphibians, Reptilian, Aves, and Mammals, including humans. For the first time, using methods of light microscopy, we performed comparative morphological studies of thymic blood microvessels in animals and humans, looking for age dependence of these differences. It was found the number and area of microcirculatory bed in thymic cortex and medullary substance depends on age, taxonomic class of the animal as well as on the environmental conditions. We have also revealed age-related differences of the intra-organ vasculature in thymus, including large arteries and venous vessels. Some specific age-related changes were found for human thymic vascular bed. On the basis of our studies, we can make conclusions about functional role of age-related changes of thymic blood vessels in immunity. The results of this study are important for basic and applied biology and medicine, being of interest to researches, especially in immunology.V. Ya. YurchinskiySPb RAACIarticlethymusvertebrate animalscorrelation analysisage-related changescomparative morphologyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 20, Iss 4, Pp 571-576 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	thymus vertebrate animals correlation analysis age-related changes comparative morphology Immunologic diseases. Allergy RC581-607
spellingShingle	thymus vertebrate animals correlation analysis age-related changes comparative morphology Immunologic diseases. Allergy RC581-607 V. Ya. Yurchinskiy AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
description	At present time, the issue of age-dependence of morphological parameters of the thymus blood vessels in members of various terrestrial vertebrates classes has been poorly studied, due to the lack of comparative morphological approaches. Therefore, the main goal of our work was to specify this kind of dependences. We studied samples of thymus glands from vertebrate animals belonging to four classes: Amphibians, Reptilian, Aves, and Mammals, including humans. For the first time, using methods of light microscopy, we performed comparative morphological studies of thymic blood microvessels in animals and humans, looking for age dependence of these differences. It was found the number and area of microcirculatory bed in thymic cortex and medullary substance depends on age, taxonomic class of the animal as well as on the environmental conditions. We have also revealed age-related differences of the intra-organ vasculature in thymus, including large arteries and venous vessels. Some specific age-related changes were found for human thymic vascular bed. On the basis of our studies, we can make conclusions about functional role of age-related changes of thymic blood vessels in immunity. The results of this study are important for basic and applied biology and medicine, being of interest to researches, especially in immunology.
format	article
author	V. Ya. Yurchinskiy
author_facet	V. Ya. Yurchinskiy
author_sort	V. Ya. Yurchinskiy
title	AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
title_short	AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
title_full	AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
title_fullStr	AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
title_full_unstemmed	AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)
title_sort	age-related changes of vascular bed within thymus gland in morphological comparative range of vertebrate animals (chordata, vertebrata)
publisher	SPb RAACI
publishDate	2018
url	https://doaj.org/article/55cc5c3a088d4265a6ab2c55610c3660
work_keys_str_mv	AT vyayurchinskiy agerelatedchangesofvascularbedwithinthymusglandinmorphologicalcomparativerangeofvertebrateanimalschordatavertebrata
_version_	1718422348064882688

AGE-RELATED CHANGES OF VASCULAR BED WITHIN THYMUS GLAND IN MORPHOLOGICAL COMPARATIVE RANGE OF VERTEBRATE ANIMALS (CHORDATA, VERTEBRATA)

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