Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis
Spinal cord injury (SCI) is a devastating event characterized by severe motor, sensory, and autonomic dysfunction. Currently, there is no effective treatment. Previous studies showed neural growth factor (NGF) administration was a potential treatment for SCI. However, its targeted delivery is still...
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Main Authors: | Lei Wang, Sujie Gu, Jinlu Gan, Yi Tian, Fangcheng Zhang, Hongyang Zhao, Deqiang Lei |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/55cf910e1c174bc4b56c008f4c2d51b6 |
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