Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells.
The large tegument proteins of herpesviruses contain N-terminal cysteine proteases with potent ubiquitin and NEDD8-specific deconjugase activities, but the function of the enzymes during virus replication remains largely unknown. Using as model BPLF1, the homologue encoded by Epstein-Barr virus (EBV...
Guardado en:
Autores principales: | Stefano Gastaldello, Xinsong Chen, Simone Callegari, Maria G Masucci |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/55d18d0a347146babdef97ee65cd53de |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment
por: Hui-Ping He, et al.
Publicado: (2020) -
The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus.
por: Chung-Pei Lee, et al.
Publicado: (2012) -
Epstein-Barr virus stimulates torque teno virus replication: a possible relationship to multiple sclerosis.
por: Silvia S Borkosky, et al.
Publicado: (2012) -
The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation
por: Masahiro Yoshida, et al.
Publicado: (2017) -
Atomic structure of the Epstein-Barr virus portal
por: Cristina Machón, et al.
Publicado: (2019)