Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review

SARS CoV-2 is a β-coronavirus responsible for the current COVID-19 pandemic. Although there is increase severity and mortality described in the elderly population and people with co-morbidities, all age groups are susceptible to COVID-19. Recent data showed that obesity has also emerged as a signifi...

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Autores principales:	Sekhar Reddy, Mohd Ashraf Ganie, Parvaiz A. Koul, Tajali Sahar, Shaista Showkat
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Materias:	sars cov-2 covid-19 obesity and mortality General works R5-130.5 Science Q
Acceso en línea:	https://doaj.org/article/55d3b504ba5941b4ae1072843263c2a2
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spelling	oai:doaj.org-article:55d3b504ba5941b4ae1072843263c2a22021-12-04T00:21:35ZObesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review0379-038X2454-563510.1055/s-0041-1736506https://doaj.org/article/55d3b504ba5941b4ae1072843263c2a22021-12-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1736506https://doaj.org/toc/0379-038Xhttps://doaj.org/toc/2454-5635SARS CoV-2 is a β-coronavirus responsible for the current COVID-19 pandemic. Although there is increase severity and mortality described in the elderly population and people with co-morbidities, all age groups are susceptible to COVID-19. Recent data showed that obesity has also emerged as a significant risk factor for COVID-19 mortality. As per the WHO, most of the world's population lives in countries where obesity is highly prevalent. In this context, we aimed to review various studies that showed obesity as an independent risk factor for mortality in SARS CoV-2 infection. We followed the PRISMA guidelines to search for two databases including PubMed and Google Scholar using the key terms “COVID-19, OBES* and MORTALITY,” SARS CoV-2, OBES* and MORTALITY” “COVID-19, OBESITY, and MORTALITY,” SARS Cov-2, OBESITY and MORTALITY,” respectively, up to August 3, 2020. Twelve studies were finally included in this review after applying inclusion and exclusion criteria. All 12 studies included in the review consistently showed that obesity is a risk factor for mortality in patients with SARS CoV-2 infection. These studies have also shown evidence that obesity leads to increased hospitalization, ICU admission, increased need for mechanical ventilation, and poor prognosis among patients with SARS CoV-2 infection. Obesity is an independent risk factor for mortality in patients infected with this novel coronavirus. Appropriate triage, monitoring, and vigilance are required while dealing with individuals with obesity with SARS CoV2 infection, especially in the young obese population. More epidemiological studies need to be done taking BMI also into consideration in COVID-19 patients to find the exact cause of increased severity and mortality and develop appropriate preventive and therapeutic strategies.Sekhar ReddyMohd Ashraf GanieParvaiz A. KoulTajali SaharShaista ShowkatThieme Medical and Scientific Publishers Pvt. Ltd.articlesars cov-2covid-19obesity and mortalityGeneral worksR5-130.5ScienceQENAnnals of the National Academy of Medical Sciences (India) (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sars cov-2 covid-19 obesity and mortality General works R5-130.5 Science Q
spellingShingle	sars cov-2 covid-19 obesity and mortality General works R5-130.5 Science Q Sekhar Reddy Mohd Ashraf Ganie Parvaiz A. Koul Tajali Sahar Shaista Showkat Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
description	SARS CoV-2 is a β-coronavirus responsible for the current COVID-19 pandemic. Although there is increase severity and mortality described in the elderly population and people with co-morbidities, all age groups are susceptible to COVID-19. Recent data showed that obesity has also emerged as a significant risk factor for COVID-19 mortality. As per the WHO, most of the world's population lives in countries where obesity is highly prevalent. In this context, we aimed to review various studies that showed obesity as an independent risk factor for mortality in SARS CoV-2 infection. We followed the PRISMA guidelines to search for two databases including PubMed and Google Scholar using the key terms “COVID-19, OBES* and MORTALITY,” SARS CoV-2, OBES* and MORTALITY” “COVID-19, OBESITY, and MORTALITY,” SARS Cov-2, OBESITY and MORTALITY,” respectively, up to August 3, 2020. Twelve studies were finally included in this review after applying inclusion and exclusion criteria. All 12 studies included in the review consistently showed that obesity is a risk factor for mortality in patients with SARS CoV-2 infection. These studies have also shown evidence that obesity leads to increased hospitalization, ICU admission, increased need for mechanical ventilation, and poor prognosis among patients with SARS CoV-2 infection. Obesity is an independent risk factor for mortality in patients infected with this novel coronavirus. Appropriate triage, monitoring, and vigilance are required while dealing with individuals with obesity with SARS CoV2 infection, especially in the young obese population. More epidemiological studies need to be done taking BMI also into consideration in COVID-19 patients to find the exact cause of increased severity and mortality and develop appropriate preventive and therapeutic strategies.
format	article
author	Sekhar Reddy Mohd Ashraf Ganie Parvaiz A. Koul Tajali Sahar Shaista Showkat
author_facet	Sekhar Reddy Mohd Ashraf Ganie Parvaiz A. Koul Tajali Sahar Shaista Showkat
author_sort	Sekhar Reddy
title	Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
title_short	Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
title_full	Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
title_fullStr	Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
title_full_unstemmed	Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review
title_sort	obesity, a risk factor for mortality in sars cov-2 infection: a narrative systematic review
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2021
url	https://doaj.org/article/55d3b504ba5941b4ae1072843263c2a2
work_keys_str_mv	AT sekharreddy obesityariskfactorformortalityinsarscov2infectionanarrativesystematicreview AT mohdashrafganie obesityariskfactorformortalityinsarscov2infectionanarrativesystematicreview AT parvaizakoul obesityariskfactorformortalityinsarscov2infectionanarrativesystematicreview AT tajalisahar obesityariskfactorformortalityinsarscov2infectionanarrativesystematicreview AT shaistashowkat obesityariskfactorformortalityinsarscov2infectionanarrativesystematicreview
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Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review

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