Reliable quantification of protein expression and cellular localization in histological sections.

In targeted therapy, patient tumors are analyzed for aberrant activations of core cancer pathways, monitored based on biomarker expression, to ensure efficient treatment. Thus, diagnosis and therapeutic decisions are often based on the status of biomarkers determined by immunohistochemistry in combi...

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Bibliographic Details
Main Authors: Michaela Schlederer, Kristina M Mueller, Johannes Haybaeck, Susanne Heider, Nicole Huttary, Margit Rosner, Markus Hengstschläger, Richard Moriggl, Helmut Dolznig, Lukas Kenner
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/55ff4d29db5a4f3aaf3c489eaf18cef2
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