Disruption of neuronal autophagy by infected microglia results in neurodegeneration.
There is compelling evidence to support the idea that autophagy has a protective function in neurons and its disruption results in neurodegenerative disorders. Neuronal damage is well-documented in the brains of HIV-infected individuals, and evidence of inflammation, oxidative stress, damage to syna...
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Autores principales: | Mehrdad Alirezaei, William B Kiosses, Claudia T Flynn, Nathan R Brady, Howard S Fox |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/56019c7dd51c4684b54b36e56a5dad79 |
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