Disruption of neuronal autophagy by infected microglia results in neurodegeneration.

There is compelling evidence to support the idea that autophagy has a protective function in neurons and its disruption results in neurodegenerative disorders. Neuronal damage is well-documented in the brains of HIV-infected individuals, and evidence of inflammation, oxidative stress, damage to syna...

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Autores principales: Mehrdad Alirezaei, William B Kiosses, Claudia T Flynn, Nathan R Brady, Howard S Fox
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/56019c7dd51c4684b54b36e56a5dad79
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