The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress

Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors. This study suggests that stress sensing and response of persisters may be targeted as an antimicrobial strategy.

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Detalles Bibliográficos
Autores principales: Marc Schulte, Katharina Olschewski, Michael Hensel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/560cb28cf26948cfa5a3b519177265d6
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Sumario:Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors. This study suggests that stress sensing and response of persisters may be targeted as an antimicrobial strategy.