The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress

Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors. This study suggests that stress sensing and response of persisters may be targeted as an antimicrobial strategy.

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Autores principales: Marc Schulte, Katharina Olschewski, Michael Hensel
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/560cb28cf26948cfa5a3b519177265d6
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spelling oai:doaj.org-article:560cb28cf26948cfa5a3b519177265d62021-12-02T15:38:22ZThe protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress10.1038/s42003-021-02049-62399-3642https://doaj.org/article/560cb28cf26948cfa5a3b519177265d62021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02049-6https://doaj.org/toc/2399-3642Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors. This study suggests that stress sensing and response of persisters may be targeted as an antimicrobial strategy.Marc SchulteKatharina OlschewskiMichael HenselNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Marc Schulte
Katharina Olschewski
Michael Hensel
The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
description Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors. This study suggests that stress sensing and response of persisters may be targeted as an antimicrobial strategy.
format article
author Marc Schulte
Katharina Olschewski
Michael Hensel
author_facet Marc Schulte
Katharina Olschewski
Michael Hensel
author_sort Marc Schulte
title The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
title_short The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
title_full The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
title_fullStr The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
title_full_unstemmed The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
title_sort protected physiological state of intracellular salmonella enterica persisters reduces host cell-imposed stress
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/560cb28cf26948cfa5a3b519177265d6
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