Prescreening clinical trial volunteers using an online personality questionnaire

Fiona Patrick,1 Allan H Young1,2 Steven CR Williams,2,3 Adam M Perkins1,2 1Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK; 2National Institute for Health Research Biomedical Research Centre, South London...

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Autores principales:	Patrick F, Young AH, Williams SCR, Perkins AM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Recruitment Pre-screening Personality Mental health Clinical Trials Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/560e0eb5b47c4ab0a9954c3652342e85
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spelling	oai:doaj.org-article:560e0eb5b47c4ab0a9954c3652342e852021-12-02T04:47:00ZPrescreening clinical trial volunteers using an online personality questionnaire1178-2021https://doaj.org/article/560e0eb5b47c4ab0a9954c3652342e852018-09-01T00:00:00Zhttps://www.dovepress.com/prescreening-clinical-trial-volunteers-using-an-online-personality-que-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Fiona Patrick,1 Allan H Young1,2 Steven CR Williams,2,3 Adam M Perkins1,2 1Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK; 2National Institute for Health Research Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK; 3Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK Background: The cost of a clinical trial is affected by the efficiency of participant recruitment. It would be desirable to create a prescreening method that identifies appropriate candidates for full screening, in order to prevent inconvenience for both trial and volunteers. This study presents an online prescreening tool for this purpose. Methods: In order to facilitate recruitment of 24 individuals meeting the criteria for generalized anxiety disorder to a pharmacological functional magnetic resonance imaging trial, we created an online personality questionnaire that generated a personality profile for each respondent and screened for the trial’s basic criteria. Results: Our online platform screened 6,293 people for anxious personality traits in 1 year. A total of 862 eligible individuals were identified through this route, each of whom automatically received an email invitation to contact the study team for further telephone screening, if interested. Of those, 266 individuals contacted the team and 173 were telephone screened, with 53 attending the study site for medical checks. Twenty-eight individuals were fully eligible, and 24 completed the trial. This permitted completion on time and on budget. Conclusion: Our online prescreening personality questionnaire platform did not remove the need for telephone screening or onsite medical checks, but increased the efficiency of recruitment through noninvasive identification of those meeting key requirements. Thus, our platform is a useful recruitment technique for clinical trials and is time-saving for both the trial and potential participants. Keywords: recruitment, prescreening, personality, mental health, clinical trialsPatrick FYoung AHWilliams SCRPerkins AMDove Medical PressarticleRecruitmentPre-screeningPersonalityMental healthClinical TrialsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 2297-2303 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Recruitment Pre-screening Personality Mental health Clinical Trials Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Recruitment Pre-screening Personality Mental health Clinical Trials Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Patrick F Young AH Williams SCR Perkins AM Prescreening clinical trial volunteers using an online personality questionnaire
description	Fiona Patrick,1 Allan H Young1,2 Steven CR Williams,2,3 Adam M Perkins1,2 1Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK; 2National Institute for Health Research Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK; 3Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK Background: The cost of a clinical trial is affected by the efficiency of participant recruitment. It would be desirable to create a prescreening method that identifies appropriate candidates for full screening, in order to prevent inconvenience for both trial and volunteers. This study presents an online prescreening tool for this purpose. Methods: In order to facilitate recruitment of 24 individuals meeting the criteria for generalized anxiety disorder to a pharmacological functional magnetic resonance imaging trial, we created an online personality questionnaire that generated a personality profile for each respondent and screened for the trial’s basic criteria. Results: Our online platform screened 6,293 people for anxious personality traits in 1 year. A total of 862 eligible individuals were identified through this route, each of whom automatically received an email invitation to contact the study team for further telephone screening, if interested. Of those, 266 individuals contacted the team and 173 were telephone screened, with 53 attending the study site for medical checks. Twenty-eight individuals were fully eligible, and 24 completed the trial. This permitted completion on time and on budget. Conclusion: Our online prescreening personality questionnaire platform did not remove the need for telephone screening or onsite medical checks, but increased the efficiency of recruitment through noninvasive identification of those meeting key requirements. Thus, our platform is a useful recruitment technique for clinical trials and is time-saving for both the trial and potential participants. Keywords: recruitment, prescreening, personality, mental health, clinical trials
format	article
author	Patrick F Young AH Williams SCR Perkins AM
author_facet	Patrick F Young AH Williams SCR Perkins AM
author_sort	Patrick F
title	Prescreening clinical trial volunteers using an online personality questionnaire
title_short	Prescreening clinical trial volunteers using an online personality questionnaire
title_full	Prescreening clinical trial volunteers using an online personality questionnaire
title_fullStr	Prescreening clinical trial volunteers using an online personality questionnaire
title_full_unstemmed	Prescreening clinical trial volunteers using an online personality questionnaire
title_sort	prescreening clinical trial volunteers using an online personality questionnaire
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/560e0eb5b47c4ab0a9954c3652342e85
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_version_	1718401005489487872

Prescreening clinical trial volunteers using an online personality questionnaire

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