Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray
Thomas I Mulcahey,1 James E Coad,2 Wei Li Fan,1 Daniel J Grasso,1 Brian M Hanley,1 Heather V Hawkes,1 Sean A McDermott,1 John P O’Connor,1 Ellen E Sheets,1 Charles J Vadala1 1CSA Medical Inc., Lexington, MA, 2Pathology Laboratory for Translational Medicine, West Virginia University, Morgan...
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Dove Medical Press
2017
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oai:doaj.org-article:560f113c487f4b9280aef9efea8787332021-12-02T00:07:13ZMetered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray1179-1470https://doaj.org/article/560f113c487f4b9280aef9efea8787332017-02-01T00:00:00Zhttps://www.dovepress.com/metered-cryospraytrade-a-novel-uniform-controlled-and-consistent-in-vi-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Thomas I Mulcahey,1 James E Coad,2 Wei Li Fan,1 Daniel J Grasso,1 Brian M Hanley,1 Heather V Hawkes,1 Sean A McDermott,1 John P O’Connor,1 Ellen E Sheets,1 Charles J Vadala1 1CSA Medical Inc., Lexington, MA, 2Pathology Laboratory for Translational Medicine, West Virginia University, Morgantown, WV, USA Abstract: In this article, a novel cryotherapy approach using a uniform, controlled, and consistent in vivo application of liquid nitrogen (LN2) spray as a Metered Cryospray™ (MCS) process is described. Although MCS may be used for many potential clinical applications, this paper focuses on the development that led to the controlled and consistent delivery of radial LN2 cryogen spray in order to generate a uniform circumferential effect and how the amount of MCS can be adapted to specifically ablate targeted diseases within a patient’s lumen such as an airway or esophagus. Keywords: Metered Cryospray™, cryoablation, rejuvenative healing, LN2 spray cryotherapyMulcahey TICoad JEFan WLGrasso DJHanley BMHawkes HVMcDermott SAO'Connor JPSheets EEVadala CJDove Medical PressarticleMetered CryosprayTM Cryoablation Rejuvenative Healing LN2 Spray CryotherapyMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol Volume 10, Pp 29-41 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Metered CryosprayTM Cryoablation Rejuvenative Healing LN2 Spray Cryotherapy Medical technology R855-855.5 |
| spellingShingle |
Metered CryosprayTM Cryoablation Rejuvenative Healing LN2 Spray Cryotherapy Medical technology R855-855.5 Mulcahey TI Coad JE Fan WL Grasso DJ Hanley BM Hawkes HV McDermott SA O'Connor JP Sheets EE Vadala CJ Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| description |
Thomas I Mulcahey,1 James E Coad,2 Wei Li Fan,1 Daniel J Grasso,1 Brian M Hanley,1 Heather V Hawkes,1 Sean A McDermott,1 John P O’Connor,1 Ellen E Sheets,1 Charles J Vadala1 1CSA Medical Inc., Lexington, MA, 2Pathology Laboratory for Translational Medicine, West Virginia University, Morgantown, WV, USA Abstract: In this article, a novel cryotherapy approach using a uniform, controlled, and consistent in vivo application of liquid nitrogen (LN2) spray as a Metered Cryospray™ (MCS) process is described. Although MCS may be used for many potential clinical applications, this paper focuses on the development that led to the controlled and consistent delivery of radial LN2 cryogen spray in order to generate a uniform circumferential effect and how the amount of MCS can be adapted to specifically ablate targeted diseases within a patient’s lumen such as an airway or esophagus. Keywords: Metered Cryospray™, cryoablation, rejuvenative healing, LN2 spray cryotherapy |
| format |
article |
| author |
Mulcahey TI Coad JE Fan WL Grasso DJ Hanley BM Hawkes HV McDermott SA O'Connor JP Sheets EE Vadala CJ |
| author_facet |
Mulcahey TI Coad JE Fan WL Grasso DJ Hanley BM Hawkes HV McDermott SA O'Connor JP Sheets EE Vadala CJ |
| author_sort |
Mulcahey TI |
| title |
Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| title_short |
Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| title_full |
Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| title_fullStr |
Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| title_full_unstemmed |
Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| title_sort |
metered cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray |
| publisher |
Dove Medical Press |
| publishDate |
2017 |
| url |
https://doaj.org/article/560f113c487f4b9280aef9efea878733 |
| work_keys_str_mv |
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1718403928884772864 |