Optogenetic dissection of ictal propagation in the hippocampal–entorhinal cortex structures

Optogenetic dissection of ictal propagation in the hippocampal–entorhinal cortex structures

The network mechanism supporting seizure spread in temporal lobe epilepsy (TLE) is only partially understood. Using optogenetic methods, Lu et al.identify a feed-forward propagation pathway of ictal discharges from the dentate gyrus/hilus to the medial entorhinal cortex in a mouse model of TLE.

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Autores principales: Yi Lu, Cheng Zhong, Lulu Wang, Pengfei Wei, Wei He, Kang Huang, Yi Zhang, Yang Zhan, Guoping Feng, Liping Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/561ad0075d1a4e4a861ac33f7a9dd9e4
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