Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

ABSTRACT Infection with human cytomegalovirus (HCMV) profoundly affects cellular metabolism. Like in tumor cells, HCMV infection increases glycolysis, and glucose carbon is shifted from the mitochondrial tricarboxylic acid cycle to the biosynthesis of fatty acids. However, unlike in many tumor cells...

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Main Authors: S. Karniely, M. P. Weekes, R. Antrobus, J. Rorbach, L. van Haute, Y. Umrania, D. L. Smith, R. J. Stanton, M. Minczuk, P. J. Lehner, J. H. Sinclair
Format: article
Language:EN
Published: American Society for Microbiology 2016
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Online Access:https://doaj.org/article/562645d9a5af495c9902557cb328f688
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