It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.

Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediat...

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Autores principales: Ana Luisa Carvalho, Dominique Fernandes
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/5627872200ee4884b8e1e5e1249a13e7
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spelling oai:doaj.org-article:5627872200ee4884b8e1e5e1249a13e72021-12-02T19:54:42ZIt takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.1544-91731545-788510.1371/journal.pbio.3001448https://doaj.org/article/5627872200ee4884b8e1e5e1249a13e72021-11-01T00:00:00Zhttps://doi.org/10.1371/journal.pbio.3001448https://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling.Ana Luisa CarvalhoDominique FernandesPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 19, Iss 11, p e3001448 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Ana Luisa Carvalho
Dominique Fernandes
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
description Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling.
format article
author Ana Luisa Carvalho
Dominique Fernandes
author_facet Ana Luisa Carvalho
Dominique Fernandes
author_sort Ana Luisa Carvalho
title It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
title_short It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
title_full It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
title_fullStr It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
title_full_unstemmed It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
title_sort it takes two to tango: concerted protein translation and degradation necessary for synaptic scaling.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/5627872200ee4884b8e1e5e1249a13e7
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