It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.
Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediat...
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Public Library of Science (PLoS)
2021
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oai:doaj.org-article:5627872200ee4884b8e1e5e1249a13e72021-12-02T19:54:42ZIt takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling.1544-91731545-788510.1371/journal.pbio.3001448https://doaj.org/article/5627872200ee4884b8e1e5e1249a13e72021-11-01T00:00:00Zhttps://doi.org/10.1371/journal.pbio.3001448https://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling.Ana Luisa CarvalhoDominique FernandesPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 19, Iss 11, p e3001448 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Ana Luisa Carvalho Dominique Fernandes It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
description |
Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling. |
format |
article |
author |
Ana Luisa Carvalho Dominique Fernandes |
author_facet |
Ana Luisa Carvalho Dominique Fernandes |
author_sort |
Ana Luisa Carvalho |
title |
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
title_short |
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
title_full |
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
title_fullStr |
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
title_full_unstemmed |
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. |
title_sort |
it takes two to tango: concerted protein translation and degradation necessary for synaptic scaling. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doaj.org/article/5627872200ee4884b8e1e5e1249a13e7 |
work_keys_str_mv |
AT analuisacarvalho ittakestwototangoconcertedproteintranslationanddegradationnecessaryforsynapticscaling AT dominiquefernandes ittakestwototangoconcertedproteintranslationanddegradationnecessaryforsynapticscaling |
_version_ |
1718375839729451008 |