Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map

Olfactory marker protein (OMP) expressed in all olfactory sensory neurons (OSN) is required for proper signal transduction and odor discrimination. Here, the authors report that OMP deletion leads to formation of glomeruli with axons from heterogeneous OSNs due to local axonal mistargeting.

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Autores principales: Dinu F. Albeanu, Allison C. Provost, Prateek Agarwal, Edward R. Soucy, Joseph D. Zak, Venkatesh N. Murthy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/562b4855157e4ab08c903da577a9a0eb
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Sumario:Olfactory marker protein (OMP) expressed in all olfactory sensory neurons (OSN) is required for proper signal transduction and odor discrimination. Here, the authors report that OMP deletion leads to formation of glomeruli with axons from heterogeneous OSNs due to local axonal mistargeting.