Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map

Olfactory marker protein (OMP) expressed in all olfactory sensory neurons (OSN) is required for proper signal transduction and odor discrimination. Here, the authors report that OMP deletion leads to formation of glomeruli with axons from heterogeneous OSNs due to local axonal mistargeting.

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Autores principales: Dinu F. Albeanu, Allison C. Provost, Prateek Agarwal, Edward R. Soucy, Joseph D. Zak, Venkatesh N. Murthy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/562b4855157e4ab08c903da577a9a0eb
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spelling oai:doaj.org-article:562b4855157e4ab08c903da577a9a0eb2021-12-02T16:50:07ZOlfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map10.1038/s41467-018-07544-92041-1723https://doaj.org/article/562b4855157e4ab08c903da577a9a0eb2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07544-9https://doaj.org/toc/2041-1723Olfactory marker protein (OMP) expressed in all olfactory sensory neurons (OSN) is required for proper signal transduction and odor discrimination. Here, the authors report that OMP deletion leads to formation of glomeruli with axons from heterogeneous OSNs due to local axonal mistargeting.Dinu F. AlbeanuAllison C. ProvostPrateek AgarwalEdward R. SoucyJoseph D. ZakVenkatesh N. MurthyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dinu F. Albeanu
Allison C. Provost
Prateek Agarwal
Edward R. Soucy
Joseph D. Zak
Venkatesh N. Murthy
Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
description Olfactory marker protein (OMP) expressed in all olfactory sensory neurons (OSN) is required for proper signal transduction and odor discrimination. Here, the authors report that OMP deletion leads to formation of glomeruli with axons from heterogeneous OSNs due to local axonal mistargeting.
format article
author Dinu F. Albeanu
Allison C. Provost
Prateek Agarwal
Edward R. Soucy
Joseph D. Zak
Venkatesh N. Murthy
author_facet Dinu F. Albeanu
Allison C. Provost
Prateek Agarwal
Edward R. Soucy
Joseph D. Zak
Venkatesh N. Murthy
author_sort Dinu F. Albeanu
title Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
title_short Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
title_full Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
title_fullStr Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
title_full_unstemmed Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
title_sort olfactory marker protein (omp) regulates formation and refinement of the olfactory glomerular map
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/562b4855157e4ab08c903da577a9a0eb
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AT edwardrsoucy olfactorymarkerproteinompregulatesformationandrefinementoftheolfactoryglomerularmap
AT josephdzak olfactorymarkerproteinompregulatesformationandrefinementoftheolfactoryglomerularmap
AT venkateshnmurthy olfactorymarkerproteinompregulatesformationandrefinementoftheolfactoryglomerularmap
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