Specialized interfaces of Smc5/6 control hinge stability and DNA association

Structural Maintenance of Chromosomes (SMC) complexes maintain genome integrity by regulating the segregation of chromosomes. Here, Altet al. describe the structure of the heterodimeric Smc5/6-hinge from fission yeast and define functional features critical for Smc5/6’s cellular function.

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Autores principales:	Aaron Alt, Hung Q. Dang, Owen S. Wells, Luis M. Polo, Matt A. Smith, Grant A. McGregor, Thomas Welte, Alan R. Lehmann, Laurence H. Pearl, Johanne M. Murray, Antony W. Oliver
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/562f81c7119947139341749f5cb5bcf7
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spelling	oai:doaj.org-article:562f81c7119947139341749f5cb5bcf72021-12-02T14:41:10ZSpecialized interfaces of Smc5/6 control hinge stability and DNA association10.1038/ncomms140112041-1723https://doaj.org/article/562f81c7119947139341749f5cb5bcf72017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14011https://doaj.org/toc/2041-1723Structural Maintenance of Chromosomes (SMC) complexes maintain genome integrity by regulating the segregation of chromosomes. Here, Altet al. describe the structure of the heterodimeric Smc5/6-hinge from fission yeast and define functional features critical for Smc5/6’s cellular function.Aaron AltHung Q. DangOwen S. WellsLuis M. PoloMatt A. SmithGrant A. McGregorThomas WelteAlan R. LehmannLaurence H. PearlJohanne M. MurrayAntony W. OliverNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aaron Alt Hung Q. Dang Owen S. Wells Luis M. Polo Matt A. Smith Grant A. McGregor Thomas Welte Alan R. Lehmann Laurence H. Pearl Johanne M. Murray Antony W. Oliver Specialized interfaces of Smc5/6 control hinge stability and DNA association
description	Structural Maintenance of Chromosomes (SMC) complexes maintain genome integrity by regulating the segregation of chromosomes. Here, Altet al. describe the structure of the heterodimeric Smc5/6-hinge from fission yeast and define functional features critical for Smc5/6’s cellular function.
format	article
author	Aaron Alt Hung Q. Dang Owen S. Wells Luis M. Polo Matt A. Smith Grant A. McGregor Thomas Welte Alan R. Lehmann Laurence H. Pearl Johanne M. Murray Antony W. Oliver
author_facet	Aaron Alt Hung Q. Dang Owen S. Wells Luis M. Polo Matt A. Smith Grant A. McGregor Thomas Welte Alan R. Lehmann Laurence H. Pearl Johanne M. Murray Antony W. Oliver
author_sort	Aaron Alt
title	Specialized interfaces of Smc5/6 control hinge stability and DNA association
title_short	Specialized interfaces of Smc5/6 control hinge stability and DNA association
title_full	Specialized interfaces of Smc5/6 control hinge stability and DNA association
title_fullStr	Specialized interfaces of Smc5/6 control hinge stability and DNA association
title_full_unstemmed	Specialized interfaces of Smc5/6 control hinge stability and DNA association
title_sort	specialized interfaces of smc5/6 control hinge stability and dna association
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/562f81c7119947139341749f5cb5bcf7
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Specialized interfaces of Smc5/6 control hinge stability and DNA association

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