Use of short-acting insulin aspart in managing older people with diabetes

Eltayeb Marouf, Alan J SinclairInstitute of Diabetes for Older People – IDOP, Bedfordshire and Hertfordshire Postgraduate Medical School, University of Bedfordshire, UKAbstract: Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups di...

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Autores principales: Eltayeb Marouf, Alan J Sinclair
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2009
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Acceso en línea:https://doaj.org/article/562fcecd86784ad9abf7f272e0332533
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spelling oai:doaj.org-article:562fcecd86784ad9abf7f272e03325332021-12-02T02:27:52ZUse of short-acting insulin aspart in managing older people with diabetes1178-1998https://doaj.org/article/562fcecd86784ad9abf7f272e03325332009-04-01T00:00:00Zhttps://www.dovepress.com/use-of-short-acting-insulin-aspart-in-managing-older-people-with-diabe-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Eltayeb Marouf, Alan J SinclairInstitute of Diabetes for Older People – IDOP, Bedfordshire and Hertfordshire Postgraduate Medical School, University of Bedfordshire, UKAbstract: Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups disproportionately affected. Treatment of older people with diabetes differs in many ways from that in younger adults since the majority have type 2 disease and are at particular risk of macrovascular rather than disabling microvascular disease. Insulin therapy, the most effective of diabetes medications, can reduce any level of elevated HBA1c if used in adequate doses. However, some clinicians are often reluctant to initiate insulin therapy in older people with diabetes mainly out of their concerns about adverse reactions to insulin, particularly hypoglycemia. There is evidence suggesting that insulin aspart appears to act similarly to regular human insulin in older people with type 2 diabetes mellitus. Insulin aspart can be used in the treatment of older people with diabetes, but this should be individualized. There is evidence that it improves postprandial glucose control, improves long-term metabolic control, reduces risk of major nocturnal hypoglycemia and increases patient satisfaction compared with soluble insulin.Keywords: older people, diabetes, insulin aspart, hypoglycemiaEltayeb MaroufAlan J SinclairDove Medical Pressarticleinsulin aspartelderlyolderdiabetesGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 4, Pp 187-190 (2009)
institution DOAJ
collection DOAJ
language EN
topic insulin aspart
elderly
older
diabetes
Geriatrics
RC952-954.6
spellingShingle insulin aspart
elderly
older
diabetes
Geriatrics
RC952-954.6
Eltayeb Marouf
Alan J Sinclair
Use of short-acting insulin aspart in managing older people with diabetes
description Eltayeb Marouf, Alan J SinclairInstitute of Diabetes for Older People – IDOP, Bedfordshire and Hertfordshire Postgraduate Medical School, University of Bedfordshire, UKAbstract: Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups disproportionately affected. Treatment of older people with diabetes differs in many ways from that in younger adults since the majority have type 2 disease and are at particular risk of macrovascular rather than disabling microvascular disease. Insulin therapy, the most effective of diabetes medications, can reduce any level of elevated HBA1c if used in adequate doses. However, some clinicians are often reluctant to initiate insulin therapy in older people with diabetes mainly out of their concerns about adverse reactions to insulin, particularly hypoglycemia. There is evidence suggesting that insulin aspart appears to act similarly to regular human insulin in older people with type 2 diabetes mellitus. Insulin aspart can be used in the treatment of older people with diabetes, but this should be individualized. There is evidence that it improves postprandial glucose control, improves long-term metabolic control, reduces risk of major nocturnal hypoglycemia and increases patient satisfaction compared with soluble insulin.Keywords: older people, diabetes, insulin aspart, hypoglycemia
format article
author Eltayeb Marouf
Alan J Sinclair
author_facet Eltayeb Marouf
Alan J Sinclair
author_sort Eltayeb Marouf
title Use of short-acting insulin aspart in managing older people with diabetes
title_short Use of short-acting insulin aspart in managing older people with diabetes
title_full Use of short-acting insulin aspart in managing older people with diabetes
title_fullStr Use of short-acting insulin aspart in managing older people with diabetes
title_full_unstemmed Use of short-acting insulin aspart in managing older people with diabetes
title_sort use of short-acting insulin aspart in managing older people with diabetes
publisher Dove Medical Press
publishDate 2009
url https://doaj.org/article/562fcecd86784ad9abf7f272e0332533
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