IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN

Objective: To find out the association between iron deficiency anemia and febrile seizures in children. Study Design: Analytical: case-control study. Place and Duration of Study: The study was conducted at Paediatrics department, Pak Emirates Military Hospital Rawalpindi, from May 2013 till Oct 2...

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Autores principales: Abdul Wahid Hussain, Abrar Ul Haq, Sohail Shahzad, Bilal Murtaza, Umar Nawaz, Munir Akmal Lodhi
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Publicado: Army Medical College Rawalpindi 2018
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Acceso en línea:https://doaj.org/article/56374e2088dc4ec9af230c1a05882fef
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spelling oai:doaj.org-article:56374e2088dc4ec9af230c1a05882fef2021-12-02T06:58:17ZIRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN0030-96482411-8842https://doaj.org/article/56374e2088dc4ec9af230c1a05882fef2018-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2311/2006https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To find out the association between iron deficiency anemia and febrile seizures in children. Study Design: Analytical: case-control study. Place and Duration of Study: The study was conducted at Paediatrics department, Pak Emirates Military Hospital Rawalpindi, from May 2013 till Oct 2013. Material and Methods: Two Hundred patients were selected through non probability consecutive sampling, one hundred in each group i.e. patients with febrile seizures and patients without febrile seizures. The blood sample of cases and controls were taken at the time of admission and was sent for assessment of hemoglobin (Hb), serum ferritin level, mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV). The samples were analyzed for iron deficiency anemia and compared in both groups (patients with febrile seizures and those without febrile seizures). Results: In the febrile seizures group 58 (58%) were anemic with a hemoglobin level less than 10gm/dL and 59 (59%) had a low plasma ferritin of less than 10ng/dL. In the control group 39 (39%) were anemic with a hemoglobin level less than 10gm/dL and 26 (26%) had a plasma ferritin of less than 10ng/dL. The frequency of anemia with low MCV, MCHC and serum ferritin was more in the febrile seizure group 38% as compared to 20% in controls (p-value = 0.002). Conclusion: The children with febrile seizures have lower hemoglobin, MCV, MCHC and serum ferritin level as compared to the control groups suggesting that iron deficiency anemia has a positive role in the pathogenesis of febrile seizures.Abdul Wahid HussainAbrar Ul HaqSohail ShahzadBilal MurtazaUmar NawazMunir Akmal LodhiArmy Medical College Rawalpindiarticleanemiafebrile seizuresferritinMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 5, Pp 1300-1305 (2018)
institution DOAJ
collection DOAJ
language EN
topic anemia
febrile seizures
ferritin
Medicine
R
Medicine (General)
R5-920
spellingShingle anemia
febrile seizures
ferritin
Medicine
R
Medicine (General)
R5-920
Abdul Wahid Hussain
Abrar Ul Haq
Sohail Shahzad
Bilal Murtaza
Umar Nawaz
Munir Akmal Lodhi
IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
description Objective: To find out the association between iron deficiency anemia and febrile seizures in children. Study Design: Analytical: case-control study. Place and Duration of Study: The study was conducted at Paediatrics department, Pak Emirates Military Hospital Rawalpindi, from May 2013 till Oct 2013. Material and Methods: Two Hundred patients were selected through non probability consecutive sampling, one hundred in each group i.e. patients with febrile seizures and patients without febrile seizures. The blood sample of cases and controls were taken at the time of admission and was sent for assessment of hemoglobin (Hb), serum ferritin level, mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV). The samples were analyzed for iron deficiency anemia and compared in both groups (patients with febrile seizures and those without febrile seizures). Results: In the febrile seizures group 58 (58%) were anemic with a hemoglobin level less than 10gm/dL and 59 (59%) had a low plasma ferritin of less than 10ng/dL. In the control group 39 (39%) were anemic with a hemoglobin level less than 10gm/dL and 26 (26%) had a plasma ferritin of less than 10ng/dL. The frequency of anemia with low MCV, MCHC and serum ferritin was more in the febrile seizure group 38% as compared to 20% in controls (p-value = 0.002). Conclusion: The children with febrile seizures have lower hemoglobin, MCV, MCHC and serum ferritin level as compared to the control groups suggesting that iron deficiency anemia has a positive role in the pathogenesis of febrile seizures.
format article
author Abdul Wahid Hussain
Abrar Ul Haq
Sohail Shahzad
Bilal Murtaza
Umar Nawaz
Munir Akmal Lodhi
author_facet Abdul Wahid Hussain
Abrar Ul Haq
Sohail Shahzad
Bilal Murtaza
Umar Nawaz
Munir Akmal Lodhi
author_sort Abdul Wahid Hussain
title IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
title_short IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
title_full IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
title_fullStr IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
title_full_unstemmed IRON DEFICIENCY ANEMIA – A RISK FACTOR FOR FEBRILE SEIZURES IN CHILDREN
title_sort iron deficiency anemia – a risk factor for febrile seizures in children
publisher Army Medical College Rawalpindi
publishDate 2018
url https://doaj.org/article/56374e2088dc4ec9af230c1a05882fef
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