Expansion of microsatellites on evolutionary young Y chromosome.

Sex chromosomes are an ideal system to study processes connected with suppressed recombination. We found evidence of microsatellite expansion, on the relatively young Y chromosome of the dioecious plant sorrel (Rumex acetosa, XY1Y2 system), but no such expansion on the more ancient Y chromosomes of...

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Autores principales:	Eduard Kejnovský, Monika Michalovova, Pavlina Steflova, Iva Kejnovska, Susana Manzano, Roman Hobza, Zdenek Kubat, Jan Kovarik, Manuel Jamilena, Boris Vyskot
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5639a3cb6d3e429d85adebb090474832
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spelling	oai:doaj.org-article:5639a3cb6d3e429d85adebb0904748322021-11-18T08:01:20ZExpansion of microsatellites on evolutionary young Y chromosome.1932-620310.1371/journal.pone.0045519https://doaj.org/article/5639a3cb6d3e429d85adebb0904748322013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23341866/?tool=EBIhttps://doaj.org/toc/1932-6203Sex chromosomes are an ideal system to study processes connected with suppressed recombination. We found evidence of microsatellite expansion, on the relatively young Y chromosome of the dioecious plant sorrel (Rumex acetosa, XY1Y2 system), but no such expansion on the more ancient Y chromosomes of liverwort (Marchantia polymorpha) and human. The most expanding motifs were AC and AAC, which also showed periodicity of array length, indicating the importance of beginnings and ends of arrays. Our data indicate that abundance of microsatellites in genomes depends on the inherent expansion potential of specific motifs, which could be related to their stability and ability to adopt unusual DNA conformations. We also found that the abundance of microsatellites is higher in the neighborhood of transposable elements (TEs) suggesting that microsatellites are probably targets for TE insertions. This evidence suggests that microsatellite expansion is an early event shaping the Y chromosome where this process is not opposed by recombination, while accumulation of TEs and chromosome shrinkage predominate later.Eduard KejnovskýMonika MichalovovaPavlina SteflovaIva KejnovskaSusana ManzanoRoman HobzaZdenek KubatJan KovarikManuel JamilenaBoris VyskotPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 1, p e45519 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Eduard Kejnovský Monika Michalovova Pavlina Steflova Iva Kejnovska Susana Manzano Roman Hobza Zdenek Kubat Jan Kovarik Manuel Jamilena Boris Vyskot Expansion of microsatellites on evolutionary young Y chromosome.
description	Sex chromosomes are an ideal system to study processes connected with suppressed recombination. We found evidence of microsatellite expansion, on the relatively young Y chromosome of the dioecious plant sorrel (Rumex acetosa, XY1Y2 system), but no such expansion on the more ancient Y chromosomes of liverwort (Marchantia polymorpha) and human. The most expanding motifs were AC and AAC, which also showed periodicity of array length, indicating the importance of beginnings and ends of arrays. Our data indicate that abundance of microsatellites in genomes depends on the inherent expansion potential of specific motifs, which could be related to their stability and ability to adopt unusual DNA conformations. We also found that the abundance of microsatellites is higher in the neighborhood of transposable elements (TEs) suggesting that microsatellites are probably targets for TE insertions. This evidence suggests that microsatellite expansion is an early event shaping the Y chromosome where this process is not opposed by recombination, while accumulation of TEs and chromosome shrinkage predominate later.
format	article
author	Eduard Kejnovský Monika Michalovova Pavlina Steflova Iva Kejnovska Susana Manzano Roman Hobza Zdenek Kubat Jan Kovarik Manuel Jamilena Boris Vyskot
author_facet	Eduard Kejnovský Monika Michalovova Pavlina Steflova Iva Kejnovska Susana Manzano Roman Hobza Zdenek Kubat Jan Kovarik Manuel Jamilena Boris Vyskot
author_sort	Eduard Kejnovský
title	Expansion of microsatellites on evolutionary young Y chromosome.
title_short	Expansion of microsatellites on evolutionary young Y chromosome.
title_full	Expansion of microsatellites on evolutionary young Y chromosome.
title_fullStr	Expansion of microsatellites on evolutionary young Y chromosome.
title_full_unstemmed	Expansion of microsatellites on evolutionary young Y chromosome.
title_sort	expansion of microsatellites on evolutionary young y chromosome.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/5639a3cb6d3e429d85adebb090474832
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Expansion of microsatellites on evolutionary young Y chromosome.

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