Mycoplasma infection and ocular surface diseases: a nationwide cohort study

Abstract Whether patients with Mycoplasma infection have an increased risk of ocular surface ulcers. Using a nation-wide database, we identified patients with a new diagnosis of Mycoplasma infection between 1997 and 2013, and compared them with age-, sex-, and index year-matched subjects without the...

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Autores principales:	Li-Ju Lai, Vincent Chin-Hung Chen, Yao-Hsu Yang, Kai-Liang Kao, Ko-Jung Chen, Ying-Ching Wang, Shu-I Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/563b5e13107542d1985e0a4f3fd7bc52
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spelling	oai:doaj.org-article:563b5e13107542d1985e0a4f3fd7bc522021-11-28T12:21:19ZMycoplasma infection and ocular surface diseases: a nationwide cohort study10.1038/s41598-021-01941-92045-2322https://doaj.org/article/563b5e13107542d1985e0a4f3fd7bc522021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01941-9https://doaj.org/toc/2045-2322Abstract Whether patients with Mycoplasma infection have an increased risk of ocular surface ulcers. Using a nation-wide database, we identified patients with a new diagnosis of Mycoplasma infection between 1997 and 2013, and compared them with age-, sex-, and index year-matched subjects without the infection. Cox proportional regression was performed to compare the risk of corneal diseases between the two cohorts. The incidence of corneal diseases was significantly higher in the 4223 patients with Mycoplasma infection than in the 16,892 patients without (7.28 vs. 5.94 per 1000 person-years, P < 0.01). The adjusted hazard ratio for the risk of corneal diseases in the study cohort was 1.21 times higher (95% CI 1.02–1.44) than that in the comparison cohort. Mycoplasma infection might be a predisposing factor for patients with keratitis.Li-Ju LaiVincent Chin-Hung ChenYao-Hsu YangKai-Liang KaoKo-Jung ChenYing-Ching WangShu-I WuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Li-Ju Lai Vincent Chin-Hung Chen Yao-Hsu Yang Kai-Liang Kao Ko-Jung Chen Ying-Ching Wang Shu-I Wu Mycoplasma infection and ocular surface diseases: a nationwide cohort study
description	Abstract Whether patients with Mycoplasma infection have an increased risk of ocular surface ulcers. Using a nation-wide database, we identified patients with a new diagnosis of Mycoplasma infection between 1997 and 2013, and compared them with age-, sex-, and index year-matched subjects without the infection. Cox proportional regression was performed to compare the risk of corneal diseases between the two cohorts. The incidence of corneal diseases was significantly higher in the 4223 patients with Mycoplasma infection than in the 16,892 patients without (7.28 vs. 5.94 per 1000 person-years, P < 0.01). The adjusted hazard ratio for the risk of corneal diseases in the study cohort was 1.21 times higher (95% CI 1.02–1.44) than that in the comparison cohort. Mycoplasma infection might be a predisposing factor for patients with keratitis.
format	article
author	Li-Ju Lai Vincent Chin-Hung Chen Yao-Hsu Yang Kai-Liang Kao Ko-Jung Chen Ying-Ching Wang Shu-I Wu
author_facet	Li-Ju Lai Vincent Chin-Hung Chen Yao-Hsu Yang Kai-Liang Kao Ko-Jung Chen Ying-Ching Wang Shu-I Wu
author_sort	Li-Ju Lai
title	Mycoplasma infection and ocular surface diseases: a nationwide cohort study
title_short	Mycoplasma infection and ocular surface diseases: a nationwide cohort study
title_full	Mycoplasma infection and ocular surface diseases: a nationwide cohort study
title_fullStr	Mycoplasma infection and ocular surface diseases: a nationwide cohort study
title_full_unstemmed	Mycoplasma infection and ocular surface diseases: a nationwide cohort study
title_sort	mycoplasma infection and ocular surface diseases: a nationwide cohort study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/563b5e13107542d1985e0a4f3fd7bc52
work_keys_str_mv	AT lijulai mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT vincentchinhungchen mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT yaohsuyang mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT kailiangkao mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT kojungchen mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT yingchingwang mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy AT shuiwu mycoplasmainfectionandocularsurfacediseasesanationwidecohortstudy
_version_	1718408014476607488

Mycoplasma infection and ocular surface diseases: a nationwide cohort study

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