A Biologically-validated HCV E1E2 Heterodimer Structural Model

A Biologically-validated HCV E1E2 Heterodimer Structural Model

Abstract The design of vaccine strategies and the development of drugs targeting the early stages of Hepatitis C virus (HCV) infection are hampered by the lack of structural information about its surface glycoproteins E1 and E2, the two constituents of HCV entry machinery. Despite the recent crystal...

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Autores principales: Matteo Castelli, Nicola Clementi, Jennifer Pfaff, Giuseppe A. Sautto, Roberta A. Diotti, Roberto Burioni, Benjamin J. Doranz, Matteo Dal Peraro, Massimo Clementi, Nicasio Mancini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/563bbbe9e5ee45d1a8b0876740226501
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