A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis

Among etiologies of hyperammonemic emergencies, infection must be considered in certain clinical contexts, particularly among immunocompromised individuals. Although Cryptococcus neoformans is known to be urease-producing, to our knowledge it has not previously been described as a cause of hyperammo...

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Autores principales: William B. Hannah, Gregory Nizialek, Katherine J. Dempsey, Keith B. Armitage, Shawn E. McCandless, Laura L. Konczal
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Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/56473f36fda34e729ad5ab41882a1530
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spelling oai:doaj.org-article:56473f36fda34e729ad5ab41882a15302021-11-26T04:29:31ZA novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis2214-426910.1016/j.ymgmr.2021.100825https://doaj.org/article/56473f36fda34e729ad5ab41882a15302021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214426921001208https://doaj.org/toc/2214-4269Among etiologies of hyperammonemic emergencies, infection must be considered in certain clinical contexts, particularly among immunocompromised individuals. Although Cryptococcus neoformans is known to be urease-producing, to our knowledge it has not previously been described as a cause of hyperammonemia in patients. We report an immunocompromised man with acute on chronic kidney disease with hyperammonemic crisis due to Cryptococcal meningitis and fungemia. It is important to be aware of C. neoformans as a possible cause of hyperammonemia.William B. HannahGregory NizialekKatherine J. DempseyKeith B. ArmitageShawn E. McCandlessLaura L. KonczalElsevierarticleCryptococcus neoformansHyperammonemiaMedicine (General)R5-920Biology (General)QH301-705.5ENMolecular Genetics and Metabolism Reports, Vol 29, Iss , Pp 100825- (2021)
institution DOAJ
collection DOAJ
language EN
topic Cryptococcus neoformans
Hyperammonemia
Medicine (General)
R5-920
Biology (General)
QH301-705.5
spellingShingle Cryptococcus neoformans
Hyperammonemia
Medicine (General)
R5-920
Biology (General)
QH301-705.5
William B. Hannah
Gregory Nizialek
Katherine J. Dempsey
Keith B. Armitage
Shawn E. McCandless
Laura L. Konczal
A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
description Among etiologies of hyperammonemic emergencies, infection must be considered in certain clinical contexts, particularly among immunocompromised individuals. Although Cryptococcus neoformans is known to be urease-producing, to our knowledge it has not previously been described as a cause of hyperammonemia in patients. We report an immunocompromised man with acute on chronic kidney disease with hyperammonemic crisis due to Cryptococcal meningitis and fungemia. It is important to be aware of C. neoformans as a possible cause of hyperammonemia.
format article
author William B. Hannah
Gregory Nizialek
Katherine J. Dempsey
Keith B. Armitage
Shawn E. McCandless
Laura L. Konczal
author_facet William B. Hannah
Gregory Nizialek
Katherine J. Dempsey
Keith B. Armitage
Shawn E. McCandless
Laura L. Konczal
author_sort William B. Hannah
title A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
title_short A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
title_full A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
title_fullStr A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
title_full_unstemmed A novel cause of emergent hyperammonemia: Cryptococcal fungemia and meningitis
title_sort novel cause of emergent hyperammonemia: cryptococcal fungemia and meningitis
publisher Elsevier
publishDate 2021
url https://doaj.org/article/56473f36fda34e729ad5ab41882a1530
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