Robust Analysis of Fluxes in Genome-Scale Metabolic Pathways
Abstract Constraint-based optimization, such as flux balance analysis (FBA), has become a standard systems-biology computational method to study cellular metabolisms that are assumed to be in a steady state of optimal growth. The methods are based on optimization while assuming (i) equilibrium of a...
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Autores principales: | Michael MacGillivray, Amy Ko, Emily Gruber, Miranda Sawyer, Eivind Almaas, Allen Holder |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/564842ef1a2348a58192b8aacef1b541 |
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