Common genetic variation in ETV6 is associated with colorectal cancer susceptibility
Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell prol...
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Nature Portfolio
2016
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| Acceso en línea: | https://doaj.org/article/564a923051f1417ea746e24f251160a4 |
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oai:doaj.org-article:564a923051f1417ea746e24f251160a42021-12-02T16:56:46ZCommon genetic variation in ETV6 is associated with colorectal cancer susceptibility10.1038/ncomms114782041-1723https://doaj.org/article/564a923051f1417ea746e24f251160a42016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11478https://doaj.org/toc/2041-1723Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro.Meilin WangDongying GuMulong DuZhi XuSuzhan ZhangLingjun ZhuJiachun LuRui ZhangJinliang XingXiaoping MiaoHaiyan ChuZhibin HuLei YangCuiju TangLei PanHaina DuJian ZhaoJiangbo DuNa TongJielin SunHongbing ShenJianfeng XuZhengdong ZhangJinfei ChenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Meilin Wang Dongying Gu Mulong Du Zhi Xu Suzhan Zhang Lingjun Zhu Jiachun Lu Rui Zhang Jinliang Xing Xiaoping Miao Haiyan Chu Zhibin Hu Lei Yang Cuiju Tang Lei Pan Haina Du Jian Zhao Jiangbo Du Na Tong Jielin Sun Hongbing Shen Jianfeng Xu Zhengdong Zhang Jinfei Chen Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| description |
Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro. |
| format |
article |
| author |
Meilin Wang Dongying Gu Mulong Du Zhi Xu Suzhan Zhang Lingjun Zhu Jiachun Lu Rui Zhang Jinliang Xing Xiaoping Miao Haiyan Chu Zhibin Hu Lei Yang Cuiju Tang Lei Pan Haina Du Jian Zhao Jiangbo Du Na Tong Jielin Sun Hongbing Shen Jianfeng Xu Zhengdong Zhang Jinfei Chen |
| author_facet |
Meilin Wang Dongying Gu Mulong Du Zhi Xu Suzhan Zhang Lingjun Zhu Jiachun Lu Rui Zhang Jinliang Xing Xiaoping Miao Haiyan Chu Zhibin Hu Lei Yang Cuiju Tang Lei Pan Haina Du Jian Zhao Jiangbo Du Na Tong Jielin Sun Hongbing Shen Jianfeng Xu Zhengdong Zhang Jinfei Chen |
| author_sort |
Meilin Wang |
| title |
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| title_short |
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| title_full |
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| title_fullStr |
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| title_full_unstemmed |
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility |
| title_sort |
common genetic variation in etv6 is associated with colorectal cancer susceptibility |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/564a923051f1417ea746e24f251160a4 |
| work_keys_str_mv |
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