Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

Extracellular vesicles are released from cells and permit communication between different cell types. Here, the authors identify that the FDA approved antibiotic sulfisoxazole, can block the release of these vesicles in breast cancer cells resulting in reduced cell growth in vitro and in vivo.

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Autores principales:	Eun-Ju Im, Chan-Hyeong Lee, Pyong-Gon Moon, Gunassekaran Gowri Rangaswamy, Byungheon Lee, Jae Man Lee, Jae-Chul Lee, Jun-Goo Jee, Jong-Sup Bae, Taeg-Kyu Kwon, Keon-Wook Kang, Myeong-Seon Jeong, Joo-Eun Lee, Hyun-Suk Jung, Hyun-Joo Ro, Sangmi Jun, Wonku Kang, Seung-Yong Seo, Young-Eun Cho, Byoung-Joon Song, Moon-Chang Baek
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/564a9fb0ea3542299cb37cacb0869df3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:564a9fb0ea3542299cb37cacb0869df32021-12-02T14:40:17ZSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A10.1038/s41467-019-09387-42041-1723https://doaj.org/article/564a9fb0ea3542299cb37cacb0869df32019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09387-4https://doaj.org/toc/2041-1723Extracellular vesicles are released from cells and permit communication between different cell types. Here, the authors identify that the FDA approved antibiotic sulfisoxazole, can block the release of these vesicles in breast cancer cells resulting in reduced cell growth in vitro and in vivo.Eun-Ju ImChan-Hyeong LeePyong-Gon MoonGunassekaran Gowri RangaswamyByungheon LeeJae Man LeeJae-Chul LeeJun-Goo JeeJong-Sup BaeTaeg-Kyu KwonKeon-Wook KangMyeong-Seon JeongJoo-Eun LeeHyun-Suk JungHyun-Joo RoSangmi JunWonku KangSeung-Yong SeoYoung-Eun ChoByoung-Joon SongMoon-Chang BaekNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eun-Ju Im Chan-Hyeong Lee Pyong-Gon Moon Gunassekaran Gowri Rangaswamy Byungheon Lee Jae Man Lee Jae-Chul Lee Jun-Goo Jee Jong-Sup Bae Taeg-Kyu Kwon Keon-Wook Kang Myeong-Seon Jeong Joo-Eun Lee Hyun-Suk Jung Hyun-Joo Ro Sangmi Jun Wonku Kang Seung-Yong Seo Young-Eun Cho Byoung-Joon Song Moon-Chang Baek Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
description	Extracellular vesicles are released from cells and permit communication between different cell types. Here, the authors identify that the FDA approved antibiotic sulfisoxazole, can block the release of these vesicles in breast cancer cells resulting in reduced cell growth in vitro and in vivo.
format	article
author	Eun-Ju Im Chan-Hyeong Lee Pyong-Gon Moon Gunassekaran Gowri Rangaswamy Byungheon Lee Jae Man Lee Jae-Chul Lee Jun-Goo Jee Jong-Sup Bae Taeg-Kyu Kwon Keon-Wook Kang Myeong-Seon Jeong Joo-Eun Lee Hyun-Suk Jung Hyun-Joo Ro Sangmi Jun Wonku Kang Seung-Yong Seo Young-Eun Cho Byoung-Joon Song Moon-Chang Baek
author_facet	Eun-Ju Im Chan-Hyeong Lee Pyong-Gon Moon Gunassekaran Gowri Rangaswamy Byungheon Lee Jae Man Lee Jae-Chul Lee Jun-Goo Jee Jong-Sup Bae Taeg-Kyu Kwon Keon-Wook Kang Myeong-Seon Jeong Joo-Eun Lee Hyun-Suk Jung Hyun-Joo Ro Sangmi Jun Wonku Kang Seung-Yong Seo Young-Eun Cho Byoung-Joon Song Moon-Chang Baek
author_sort	Eun-Ju Im
title	Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
title_short	Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
title_full	Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
title_fullStr	Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
title_full_unstemmed	Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
title_sort	sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor a
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/564a9fb0ea3542299cb37cacb0869df3
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Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

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