The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins

The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins

The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that mediates interactions between bacteria and their invertebrate hosts. Here, the authors catalogue eCIS loci from 1,249 prokaryotic genomes, showing enrichment in non-pathogenic environmental microbes, and identify...

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Autores principales: Alexander Martin Geller, Inbal Pollin, David Zlotkin, Aleks Danov, Nimrod Nachmias, William B. Andreopoulos, Keren Shemesh, Asaf Levy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/564af667027a4f3d80febcda2fb8b060
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spelling oai:doaj.org-article:564af667027a4f3d80febcda2fb8b0602021-12-02T17:40:28ZThe extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins10.1038/s41467-021-23777-72041-1723https://doaj.org/article/564af667027a4f3d80febcda2fb8b0602021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23777-7https://doaj.org/toc/2041-1723The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that mediates interactions between bacteria and their invertebrate hosts. Here, the authors catalogue eCIS loci from 1,249 prokaryotic genomes, showing enrichment in non-pathogenic environmental microbes, and identifying eCIS-associated toxins that inhibit the growth of bacteria and/or yeast.Alexander Martin GellerInbal PollinDavid ZlotkinAleks DanovNimrod NachmiasWilliam B. AndreopoulosKeren ShemeshAsaf LevyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander Martin Geller
Inbal Pollin
David Zlotkin
Aleks Danov
Nimrod Nachmias
William B. Andreopoulos
Keren Shemesh
Asaf Levy
The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
description The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that mediates interactions between bacteria and their invertebrate hosts. Here, the authors catalogue eCIS loci from 1,249 prokaryotic genomes, showing enrichment in non-pathogenic environmental microbes, and identifying eCIS-associated toxins that inhibit the growth of bacteria and/or yeast.
format article
author Alexander Martin Geller
Inbal Pollin
David Zlotkin
Aleks Danov
Nimrod Nachmias
William B. Andreopoulos
Keren Shemesh
Asaf Levy
author_facet Alexander Martin Geller
Inbal Pollin
David Zlotkin
Aleks Danov
Nimrod Nachmias
William B. Andreopoulos
Keren Shemesh
Asaf Levy
author_sort Alexander Martin Geller
title The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
title_short The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
title_full The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
title_fullStr The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
title_full_unstemmed The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
title_sort extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/564af667027a4f3d80febcda2fb8b060
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