Hypomethylation of Alu elements in post-menopausal women with osteoporosis.

Hypomethylation of Alu elements in post-menopausal women with osteoporosis.

A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu demeth...

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Autores principales: Pornrutsami Jintaridth, Rungsunn Tungtrongchitr, Sangchai Preutthipan, Apiwat Mutirangura
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/564dbc504e5b4d818274868d4d4d1464
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