CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement

<i>Objective:</i> To assess whether phosphorylated neurofilament heavy chain (pNfH) can discriminate different upper motor neuron (UMN) syndromes, namely, ALS, UMN-predominant ALS, primary lateral sclerosis (PLS) and hereditary spastic paraparesis (hSP) and to test the prognostic value o...

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Bibliographic Details
Main Authors: Cecilia Simonini, Elisabetta Zucchi, Roberta Bedin, Ilaria Martinelli, Giulia Gianferrari, Nicola Fini, Gianni Sorarù, Rocco Liguori, Veria Vacchiano, Jessica Mandrioli
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
motor neuron disease
neurofilaments
upper motor neuron
degeneration
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/5652ddbb3ec04dbdbfdfac055c02f307
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https://doaj.org/article/5652ddbb3ec04dbdbfdfac055c02f307

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