Lrg1 Regulates β (1,3)-Glucan Masking in <named-content content-type="genus-species">Candida albicans</named-content> through the Cek1 MAP Kinase Pathway

Lrg1 Regulates β (1,3)-Glucan Masking in <named-content content-type="genus-species">Candida albicans</named-content> through the Cek1 MAP Kinase Pathway

ABSTRACT Candida albicans is among the most prevalent opportunistic human fungal pathogens. The ability to mask the immunogenic polysaccharide β (1,3)-glucan from immune detection via a layer of mannosylated proteins is a key virulence factor of C. albicans. We previously reported that hyperactivati...

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Bibliographic Details
Main Authors: Tian Chen, Andrew S. Wagner, Robert N. Tams, James E. Eyer, Sarah J. Kauffman, Eric R. Gann, Elias J. Fernandez, Todd B. Reynolds
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
GTPase
Cdc42
Rho1
Ras1
Rac1
MAPK cascade
Microbiology
QR1-502
Online Access:https://doaj.org/article/56562271134e4311b16c16b528c26ce3
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