[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children

Objective: To study the association between the grade of reflux and urinary tract infections (UTIs) and renal scarring at the first clinical presentation of patients who underwent anti-reflux surgery. Methods: Between 2010 and 2017, 150 patients (194 renal units) who underwent anti-reflux surgery, h...

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Autores principales:	Hamdy Aboutaleb, Tamer A. Ali, Hala El-Hagrasi, Mohamed Amin El Gohary
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/565a1b36eaa94b7bb191a9414f1fa398
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spelling	oai:doaj.org-article:565a1b36eaa94b7bb191a9414f1fa3982021-12-02T10:50:52Z[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children2090-598X10.1016/j.aju.2018.10.064https://doaj.org/article/565a1b36eaa94b7bb191a9414f1fa3982018-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2090598X1830158Xhttps://doaj.org/toc/2090-598XObjective: To study the association between the grade of reflux and urinary tract infections (UTIs) and renal scarring at the first clinical presentation of patients who underwent anti-reflux surgery. Methods: Between 2010 and 2017, 150 patients (194 renal units) who underwent anti-reflux surgery, had dimercaptosuccinic acid (DMSA) renal scans preoperatively (retrospective study). The patients were classified into non-scar and scar groups according to the DMSA scan results. Moreover, cases were classified into afebrile UTI, febrile UTI, and antenatal hydronephrosis (ANH) according to the mode of presentation. We correlated the mode of presentation and the grade of reflux to the presence/absence of renal scars in both groups. Grading of reflux was (I–V) according to the International Reflux Study Committee 1987. Results: The mean follow-up was 45 months. The mode of presentation was afebrile, febrile UTIs and ANH in (50, 14) (20, 46) and (10, 10) in the non-scar and scar groups, respectively. Of the 20 patients who presented with ANH, 10 (50%) had scars. The mode of clinical presentation was correlated to the presence of renal scarring and its degree. The scar group had significantly higher grades of vesico-ureteric reflux than the non-scar group; grades I–II [40 patients, 50 units vs eight patients, 10 units], grade III [24 patients, 28 units vs 30 patients, 40 units] and grade IV–V [16 patients, 22 units vs 32 patients, 44 units] for the non-scar vs scar groups, respectively (P = 0.005). Conclusion: Renal scarring is linked to higher grades of reflux and UTIs. We advocate proper investigations of infants who have UTIs with or without fever for early detection of reflux.Hamdy AboutalebTamer A. AliHala El-HagrasiMohamed Amin El GoharyTaylor & Francis GrouparticleDiseases of the genitourinary system. UrologyRC870-923ENArab Journal of Urology, Vol 16, Iss , Pp S9- (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the genitourinary system. Urology RC870-923
spellingShingle	Diseases of the genitourinary system. Urology RC870-923 Hamdy Aboutaleb Tamer A. Ali Hala El-Hagrasi Mohamed Amin El Gohary [17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
description	Objective: To study the association between the grade of reflux and urinary tract infections (UTIs) and renal scarring at the first clinical presentation of patients who underwent anti-reflux surgery. Methods: Between 2010 and 2017, 150 patients (194 renal units) who underwent anti-reflux surgery, had dimercaptosuccinic acid (DMSA) renal scans preoperatively (retrospective study). The patients were classified into non-scar and scar groups according to the DMSA scan results. Moreover, cases were classified into afebrile UTI, febrile UTI, and antenatal hydronephrosis (ANH) according to the mode of presentation. We correlated the mode of presentation and the grade of reflux to the presence/absence of renal scars in both groups. Grading of reflux was (I–V) according to the International Reflux Study Committee 1987. Results: The mean follow-up was 45 months. The mode of presentation was afebrile, febrile UTIs and ANH in (50, 14) (20, 46) and (10, 10) in the non-scar and scar groups, respectively. Of the 20 patients who presented with ANH, 10 (50%) had scars. The mode of clinical presentation was correlated to the presence of renal scarring and its degree. The scar group had significantly higher grades of vesico-ureteric reflux than the non-scar group; grades I–II [40 patients, 50 units vs eight patients, 10 units], grade III [24 patients, 28 units vs 30 patients, 40 units] and grade IV–V [16 patients, 22 units vs 32 patients, 44 units] for the non-scar vs scar groups, respectively (P = 0.005). Conclusion: Renal scarring is linked to higher grades of reflux and UTIs. We advocate proper investigations of infants who have UTIs with or without fever for early detection of reflux.
format	article
author	Hamdy Aboutaleb Tamer A. Ali Hala El-Hagrasi Mohamed Amin El Gohary
author_facet	Hamdy Aboutaleb Tamer A. Ali Hala El-Hagrasi Mohamed Amin El Gohary
author_sort	Hamdy Aboutaleb
title	[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
title_short	[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
title_full	[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
title_fullStr	[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
title_full_unstemmed	[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
title_sort	[17] correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/565a1b36eaa94b7bb191a9414f1fa398
work_keys_str_mv	AT hamdyaboutaleb 17correlationofrenalscarringtourinarytractinfectionsandvesicouretericrefluxinchildren AT tameraali 17correlationofrenalscarringtourinarytractinfectionsandvesicouretericrefluxinchildren AT halaelhagrasi 17correlationofrenalscarringtourinarytractinfectionsandvesicouretericrefluxinchildren AT mohamedaminelgohary 17correlationofrenalscarringtourinarytractinfectionsandvesicouretericrefluxinchildren
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[17] Correlation of renal scarring to urinary tract infections and vesico-ureteric reflux in children

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