Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments

Palanivel Ganesan,1 Govindarajan Karthivashan,2 Shin Young Park,2 Joonsoo Kim,2 Dong-Kug Choi1,2 1Department of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju 27478, Republic of Korea; 2Department of App...

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Autores principales:	Ganesan P, Karthivashan G, Park S, Kim J, Choi DK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	microfluidization nanodelivery systems bioactive compounds chronic diseases Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/566373cccc81454fb1b04f6810d5beca
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spelling	oai:doaj.org-article:566373cccc81454fb1b04f6810d5beca2021-12-02T00:04:28ZMicrofluidization trends in the development of nanodelivery systems and applications in chronic disease treatments1178-2013https://doaj.org/article/566373cccc81454fb1b04f6810d5beca2018-10-01T00:00:00Zhttps://www.dovepress.com/microfluidization-trends-in-the-development-of-nanodelivery-systems-an-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Palanivel Ganesan,1 Govindarajan Karthivashan,2 Shin Young Park,2 Joonsoo Kim,2 Dong-Kug Choi1,2 1Department of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju 27478, Republic of Korea; 2Department of Applied Life Sciences, Graduate School of Konkuk University, Research Institute of Inflammatory Diseases, Chungju 27478, Republic of Korea Abstract: Plant bioactive compounds are known for their extensive health benefits and therefore have been used for generations in traditional and modern medicine to improve the health of humans. Processing and storage instabilities of the plant bioactive compounds, however, limit their bioavailability and bioaccessibility and thus lead researchers in search of novel encapsulation systems with enhanced stability, bioavailability, and bioaccessibility of encapsulated plant bioactive compounds. Recently many varieties of encapsulation methods have been used; among them, microfluidization has emerged as a novel method used for the development of delivery systems including solid lipid nanocarriers, nanoemulsions, liposomes, and so on with enhanced stability and bioavailability of encapsulated plant bioactive compounds. Therefore, the nanodelivery systems developed using microfluidization techniques have received much attention from the medical industry for their ability to facilitate controlled delivery with enhanced health benefits in the treatment of various chronic diseases. Many researchers have focused on plant bioactive compound-based delivery systems using microfluidization to enhance the bioavailability and bioaccessibility of encapsulated bioactive compounds in the treatment of various chronic diseases. This review focuses on various nanodelivery systems developed using microfluidization techniques and applications in various chronic disease treatments. Keywords: bioavailability, solid lipid nanoparticles, plant bioactive compounds, nanoemulsionsGanesan PKarthivashan GPark SKim JChoi DKDove Medical Pressarticlemicrofluidizationnanodelivery systemsbioactive compoundschronic diseasesMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 6109-6121 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	microfluidization nanodelivery systems bioactive compounds chronic diseases Medicine (General) R5-920
spellingShingle	microfluidization nanodelivery systems bioactive compounds chronic diseases Medicine (General) R5-920 Ganesan P Karthivashan G Park S Kim J Choi DK Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
description	Palanivel Ganesan,1 Govindarajan Karthivashan,2 Shin Young Park,2 Joonsoo Kim,2 Dong-Kug Choi1,2 1Department of Integrated Bio Science and Biotechnology, College of Biomedical and Health Science, Nanotechnology Research Center, Konkuk University, Chungju 27478, Republic of Korea; 2Department of Applied Life Sciences, Graduate School of Konkuk University, Research Institute of Inflammatory Diseases, Chungju 27478, Republic of Korea Abstract: Plant bioactive compounds are known for their extensive health benefits and therefore have been used for generations in traditional and modern medicine to improve the health of humans. Processing and storage instabilities of the plant bioactive compounds, however, limit their bioavailability and bioaccessibility and thus lead researchers in search of novel encapsulation systems with enhanced stability, bioavailability, and bioaccessibility of encapsulated plant bioactive compounds. Recently many varieties of encapsulation methods have been used; among them, microfluidization has emerged as a novel method used for the development of delivery systems including solid lipid nanocarriers, nanoemulsions, liposomes, and so on with enhanced stability and bioavailability of encapsulated plant bioactive compounds. Therefore, the nanodelivery systems developed using microfluidization techniques have received much attention from the medical industry for their ability to facilitate controlled delivery with enhanced health benefits in the treatment of various chronic diseases. Many researchers have focused on plant bioactive compound-based delivery systems using microfluidization to enhance the bioavailability and bioaccessibility of encapsulated bioactive compounds in the treatment of various chronic diseases. This review focuses on various nanodelivery systems developed using microfluidization techniques and applications in various chronic disease treatments. Keywords: bioavailability, solid lipid nanoparticles, plant bioactive compounds, nanoemulsions
format	article
author	Ganesan P Karthivashan G Park S Kim J Choi DK
author_facet	Ganesan P Karthivashan G Park S Kim J Choi DK
author_sort	Ganesan P
title	Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
title_short	Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
title_full	Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
title_fullStr	Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
title_full_unstemmed	Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
title_sort	microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/566373cccc81454fb1b04f6810d5beca
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Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments

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