Structural basis of arrestin-3 activation and signaling

Structural basis of arrestin-3 activation and signaling

While arrestins are mainly associated with GPCR signaling, arrestin-3 can signal independently of receptor interaction. Here the authors present the structure of arrestin-3 bound to inositol hexakisphosphate (IP6) and propose a model for arrestin-3 activation.

Saved in:
Bibliographic Details
Main Authors: Qiuyan Chen, Nicole A. Perry, Sergey A. Vishnivetskiy, Sandra Berndt, Nathaniel C. Gilbert, Ya Zhuo, Prashant K. Singh, Jonas Tholen, Melanie D. Ohi, Eugenia V. Gurevich, Chad A. Brautigam, Candice S. Klug, Vsevolod V. Gurevich, T. M. Iverson
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/5669fd07492147f39e3967f45e7f0f53
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/5669fd07492147f39e3967f45e7f0f53

Similar Items