The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature

Staphylococcus aureus pathogenicity islands (SaPIs) encode the master repressor Stl and after bacteriophage infection Stl interacts with specific phage proteins leading to a derepression of SaPIs. Here the authors provide structural insights into this family of repressors by determining the crystal...

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Autores principales: J. Rafael Ciges-Tomas, Christian Alite, Suzanne Humphrey, J. Donderis, Janine Bowring, Xavier Salvatella, José R. Penadés, Alberto Marina
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/566f46134dd3427ca48ea42f87620741
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