Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding

Epithelial sheet migration requires polarized and coordinated cell movement. Here, the authors demonstrate serum-activated collective migration followed by polarized asymmetric cell divisions in otherwise quiescent human keratinocyte monolayers in the absence of wound edges.

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Autores principales: Emma Lång, Anna Połeć, Anna Lång, Marijke Valk, Pernille Blicher, Alexander D. Rowe, Kim A. Tønseth, Catherine J. Jackson, Tor P. Utheim, Liesbeth M. C. Janssen, Jens Eriksson, Stig Ove Bøe
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/56730725888641c7b0f946697f96d47e
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spelling oai:doaj.org-article:56730725888641c7b0f946697f96d47e2021-12-02T15:33:35ZCoordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding10.1038/s41467-018-05578-72041-1723https://doaj.org/article/56730725888641c7b0f946697f96d47e2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05578-7https://doaj.org/toc/2041-1723Epithelial sheet migration requires polarized and coordinated cell movement. Here, the authors demonstrate serum-activated collective migration followed by polarized asymmetric cell divisions in otherwise quiescent human keratinocyte monolayers in the absence of wound edges.Emma LångAnna PołećAnna LångMarijke ValkPernille BlicherAlexander D. RoweKim A. TønsethCatherine J. JacksonTor P. UtheimLiesbeth M. C. JanssenJens ErikssonStig Ove BøeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emma Lång
Anna Połeć
Anna Lång
Marijke Valk
Pernille Blicher
Alexander D. Rowe
Kim A. Tønseth
Catherine J. Jackson
Tor P. Utheim
Liesbeth M. C. Janssen
Jens Eriksson
Stig Ove Bøe
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
description Epithelial sheet migration requires polarized and coordinated cell movement. Here, the authors demonstrate serum-activated collective migration followed by polarized asymmetric cell divisions in otherwise quiescent human keratinocyte monolayers in the absence of wound edges.
format article
author Emma Lång
Anna Połeć
Anna Lång
Marijke Valk
Pernille Blicher
Alexander D. Rowe
Kim A. Tønseth
Catherine J. Jackson
Tor P. Utheim
Liesbeth M. C. Janssen
Jens Eriksson
Stig Ove Bøe
author_facet Emma Lång
Anna Połeć
Anna Lång
Marijke Valk
Pernille Blicher
Alexander D. Rowe
Kim A. Tønseth
Catherine J. Jackson
Tor P. Utheim
Liesbeth M. C. Janssen
Jens Eriksson
Stig Ove Bøe
author_sort Emma Lång
title Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
title_short Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
title_full Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
title_fullStr Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
title_full_unstemmed Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
title_sort coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/56730725888641c7b0f946697f96d47e
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