Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections
Although enterovirus D68 poses a major global threat to children, neither vaccines nor therapeutics are currently available. Using Cryo-EM, Zhang et al. show that two murine-derived monoclonal antibodies with therapeutic efficacy neutralize virions via binding to the canyon region, creating steric h...
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Autores principales: | Chao Zhang, Cong Xu, Wenlong Dai, Yifan Wang, Zhi Liu, Xueyang Zhang, Xuesong Wang, Haikun Wang, Sitang Gong, Yao Cong, Zhong Huang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5675dadc248d4ebbb892c894b41bba5f |
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