Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty

Pyoderma gangrenosum is a neutrophilic dermatosis, which mimics both infection and necrotizing fasciitis, that can present after surgical interventions. We present the case of a 62-year-old male who underwent one-stage bilateral total knee arthroplasty. Nine days after the surgery, he presented with...

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Autores principales:	Reilly Loomis, PA-C, Mellanie Merrit, PA-C, Maria Alexandrovna Aleshin, MD, Grace Graw, MD, Gordon Lee, MD, Bradley Graw, MD
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Total knee arthroplasty Pyoderma gangrenosum Prosthetic joint infection Necrotizing fasciitis Pathergy Orthopedic surgery RD701-811
Acceso en línea:	https://doaj.org/article/5677bfa7e94e4f26a3e04628ac4cd70d
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spelling	oai:doaj.org-article:5677bfa7e94e4f26a3e04628ac4cd70d2021-11-14T04:33:47ZPyoderma Gangrenosum After Bilateral Total Knee Arthroplasty2352-344110.1016/j.artd.2021.07.003https://doaj.org/article/5677bfa7e94e4f26a3e04628ac4cd70d2021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2352344121001217https://doaj.org/toc/2352-3441Pyoderma gangrenosum is a neutrophilic dermatosis, which mimics both infection and necrotizing fasciitis, that can present after surgical interventions. We present the case of a 62-year-old male who underwent one-stage bilateral total knee arthroplasty. Nine days after the surgery, he presented with wound breakdown, high fever, and elevated white blood cell count. Repeated debridement was performed, and empiric antibiotics were given. All tissue cultures and aspirates remained negative throughout treatment course, and the patient remained unresponsive to therapy. The patient was eventually diagnosed with pyoderma gangrenosum after infectious etiologies were ruled out and after a skin biopsy and dermatologic consultation. His condition rapidly improved after treatment with corticosteroids, and soft-tissue defects were repaired with skin substitute and full-thickness skin grafting. In patients with aseptic wound breakdown after total knee arthroplasty, pyoderma gangrenosum is a rare but devastating complication and should be considered.Reilly Loomis, PA-CMellanie Merrit, PA-CMaria Alexandrovna Aleshin, MDGrace Graw, MDGordon Lee, MDBradley Graw, MDElsevierarticleTotal knee arthroplastyPyoderma gangrenosumProsthetic joint infectionNecrotizing fasciitisPathergyOrthopedic surgeryRD701-811ENArthroplasty Today, Vol 11, Iss , Pp 73-79 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Total knee arthroplasty Pyoderma gangrenosum Prosthetic joint infection Necrotizing fasciitis Pathergy Orthopedic surgery RD701-811
spellingShingle	Total knee arthroplasty Pyoderma gangrenosum Prosthetic joint infection Necrotizing fasciitis Pathergy Orthopedic surgery RD701-811 Reilly Loomis, PA-C Mellanie Merrit, PA-C Maria Alexandrovna Aleshin, MD Grace Graw, MD Gordon Lee, MD Bradley Graw, MD Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
description	Pyoderma gangrenosum is a neutrophilic dermatosis, which mimics both infection and necrotizing fasciitis, that can present after surgical interventions. We present the case of a 62-year-old male who underwent one-stage bilateral total knee arthroplasty. Nine days after the surgery, he presented with wound breakdown, high fever, and elevated white blood cell count. Repeated debridement was performed, and empiric antibiotics were given. All tissue cultures and aspirates remained negative throughout treatment course, and the patient remained unresponsive to therapy. The patient was eventually diagnosed with pyoderma gangrenosum after infectious etiologies were ruled out and after a skin biopsy and dermatologic consultation. His condition rapidly improved after treatment with corticosteroids, and soft-tissue defects were repaired with skin substitute and full-thickness skin grafting. In patients with aseptic wound breakdown after total knee arthroplasty, pyoderma gangrenosum is a rare but devastating complication and should be considered.
format	article
author	Reilly Loomis, PA-C Mellanie Merrit, PA-C Maria Alexandrovna Aleshin, MD Grace Graw, MD Gordon Lee, MD Bradley Graw, MD
author_facet	Reilly Loomis, PA-C Mellanie Merrit, PA-C Maria Alexandrovna Aleshin, MD Grace Graw, MD Gordon Lee, MD Bradley Graw, MD
author_sort	Reilly Loomis, PA-C
title	Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
title_short	Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
title_full	Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
title_fullStr	Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
title_full_unstemmed	Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty
title_sort	pyoderma gangrenosum after bilateral total knee arthroplasty
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/5677bfa7e94e4f26a3e04628ac4cd70d
work_keys_str_mv	AT reillyloomispac pyodermagangrenosumafterbilateraltotalkneearthroplasty AT mellaniemerritpac pyodermagangrenosumafterbilateraltotalkneearthroplasty AT mariaalexandrovnaaleshinmd pyodermagangrenosumafterbilateraltotalkneearthroplasty AT gracegrawmd pyodermagangrenosumafterbilateraltotalkneearthroplasty AT gordonleemd pyodermagangrenosumafterbilateraltotalkneearthroplasty AT bradleygrawmd pyodermagangrenosumafterbilateraltotalkneearthroplasty
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Pyoderma Gangrenosum After Bilateral Total Knee Arthroplasty

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