Region and cell-type resolved quantitative proteomic map of the human heart

The human heart is composed of distinct regions and cell types, but relatively little is known about their specific protein composition. Here, the authors present a region- and cell type-specific proteomic map of the healthy human heart, revealing functional differences and potential cell type marke...

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Autores principales: Sophia Doll, Martina Dreßen, Philipp E. Geyer, Daniel N. Itzhak, Christian Braun, Stefanie A. Doppler, Florian Meier, Marcus-Andre Deutsch, Harald Lahm, Rüdiger Lange, Markus Krane, Matthias Mann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/567eef510a6f43498199606e690bcfcb
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Sumario:The human heart is composed of distinct regions and cell types, but relatively little is known about their specific protein composition. Here, the authors present a region- and cell type-specific proteomic map of the healthy human heart, revealing functional differences and potential cell type markers.