EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS

The influence of the complex plant remedy (Urtica dioica L., Polygonum aviculare L., Achillea millefolium L., Zingiber officinalis L., Cinnamomum cassia L.) on the morphofunctional state of the liver in rats with ethanol-induced hepatitis was studied. The liver injury was simulated with 40% ethanol...

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Autores principales:	S. M. Nikolayev, Y. G. Razuvayeva, A. A. Toropova, I. P. Ubeyeva, N. V. Verlan, V. V. Ayusheyeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	urtica dioica l polygonum aviculare l achillea millefolium l zingiber officinalis l cinnamomum cassia l complex plant remedy ethanol-induced hepatitis Science Q
Acceso en línea:	https://doaj.org/article/568447dd1a7647b49128fbfce0946c75
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spelling	oai:doaj.org-article:568447dd1a7647b49128fbfce0946c752021-11-23T06:14:36ZEFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS2541-94202587-959610.12737/23812https://doaj.org/article/568447dd1a7647b49128fbfce0946c752016-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/342https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The influence of the complex plant remedy (Urtica dioica L., Polygonum aviculare L., Achillea millefolium L., Zingiber officinalis L., Cinnamomum cassia L.) on the morphofunctional state of the liver in rats with ethanol-induced hepatitis was studied. The liver injury was simulated with 40% ethanol introduction to rats in dose of 10.0 ml/kg for 7 days. The extract of the complex remedy was administered to animals in dose of 200 ml/kg for 14 days. The findings showed that the tested remedy inhibited the development of microcirculatory impairments, decreased the intensity of inflammatory infiltration and diminished the amount of hepatocytes subjected to adipose and cloudy degeneration as well as to necrotic changes. The increased amount of hypertrophied and binuclear hepatocytes in the area of the portal tract and central vein testifies reparation processes in the liver of the rats treated with the tested plant extract.S. M. NikolayevY. G. RazuvayevaA. A. ToropovaI. P. UbeyevaN. V. VerlanV. V. AyusheyevaScientific Сentre for Family Health and Human Reproduction Problemsarticleurtica dioica lpolygonum aviculare lachillea millefolium lzingiber officinalis lcinnamomum cassia lcomplex plant remedyurtica dioica lpolygonum aviculare lachillea millefolium lzingiber officinalis lcinnamomum cassia lethanol-induced hepatitisScienceQRUActa Biomedica Scientifica, Vol 1, Iss 6, Pp 167-170 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	urtica dioica l polygonum aviculare l achillea millefolium l zingiber officinalis l cinnamomum cassia l complex plant remedy urtica dioica l polygonum aviculare l achillea millefolium l zingiber officinalis l cinnamomum cassia l ethanol-induced hepatitis Science Q
spellingShingle	urtica dioica l polygonum aviculare l achillea millefolium l zingiber officinalis l cinnamomum cassia l complex plant remedy urtica dioica l polygonum aviculare l achillea millefolium l zingiber officinalis l cinnamomum cassia l ethanol-induced hepatitis Science Q S. M. Nikolayev Y. G. Razuvayeva A. A. Toropova I. P. Ubeyeva N. V. Verlan V. V. Ayusheyeva EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
description	The influence of the complex plant remedy (Urtica dioica L., Polygonum aviculare L., Achillea millefolium L., Zingiber officinalis L., Cinnamomum cassia L.) on the morphofunctional state of the liver in rats with ethanol-induced hepatitis was studied. The liver injury was simulated with 40% ethanol introduction to rats in dose of 10.0 ml/kg for 7 days. The extract of the complex remedy was administered to animals in dose of 200 ml/kg for 14 days. The findings showed that the tested remedy inhibited the development of microcirculatory impairments, decreased the intensity of inflammatory infiltration and diminished the amount of hepatocytes subjected to adipose and cloudy degeneration as well as to necrotic changes. The increased amount of hypertrophied and binuclear hepatocytes in the area of the portal tract and central vein testifies reparation processes in the liver of the rats treated with the tested plant extract.
format	article
author	S. M. Nikolayev Y. G. Razuvayeva A. A. Toropova I. P. Ubeyeva N. V. Verlan V. V. Ayusheyeva
author_facet	S. M. Nikolayev Y. G. Razuvayeva A. A. Toropova I. P. Ubeyeva N. V. Verlan V. V. Ayusheyeva
author_sort	S. M. Nikolayev
title	EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
title_short	EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
title_full	EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
title_fullStr	EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
title_full_unstemmed	EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS
title_sort	effect of complex plant remedy on the morphofunctional state of the liver of rats with ethanol-induced hepatitis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/568447dd1a7647b49128fbfce0946c75
work_keys_str_mv	AT smnikolayev effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis AT ygrazuvayeva effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis AT aatoropova effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis AT ipubeyeva effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis AT nvverlan effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis AT vvayusheyeva effectofcomplexplantremedyonthemorphofunctionalstateoftheliverofratswithethanolinducedhepatitis
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EFFECT OF COMPLEX PLANT REMEDY ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF RATS WITH ETHANOL-INDUCED HEPATITIS

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