ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria

Structural and functional analysis of mitochondria from the human parasite Toxoplasma gondii reveals that its ATP synthase assembles into cyclic hexamers, arranged together in a form of pentagonal pyramids required for maintenance of cristae morphology in Apicomplexa.

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Autores principales:	Alexander Mühleip, Rasmus Kock Flygaard, Jana Ovciarikova, Alice Lacombe, Paula Fernandes, Lilach Sheiner, Alexey Amunts
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/56947c119cc747a6b15d66b6a2139440
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spelling	oai:doaj.org-article:56947c119cc747a6b15d66b6a21394402021-12-02T11:56:18ZATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria10.1038/s41467-020-20381-z2041-1723https://doaj.org/article/56947c119cc747a6b15d66b6a21394402021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20381-zhttps://doaj.org/toc/2041-1723Structural and functional analysis of mitochondria from the human parasite Toxoplasma gondii reveals that its ATP synthase assembles into cyclic hexamers, arranged together in a form of pentagonal pyramids required for maintenance of cristae morphology in Apicomplexa.Alexander MühleipRasmus Kock FlygaardJana OvciarikovaAlice LacombePaula FernandesLilach SheinerAlexey AmuntsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander Mühleip Rasmus Kock Flygaard Jana Ovciarikova Alice Lacombe Paula Fernandes Lilach Sheiner Alexey Amunts ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
description	Structural and functional analysis of mitochondria from the human parasite Toxoplasma gondii reveals that its ATP synthase assembles into cyclic hexamers, arranged together in a form of pentagonal pyramids required for maintenance of cristae morphology in Apicomplexa.
format	article
author	Alexander Mühleip Rasmus Kock Flygaard Jana Ovciarikova Alice Lacombe Paula Fernandes Lilach Sheiner Alexey Amunts
author_facet	Alexander Mühleip Rasmus Kock Flygaard Jana Ovciarikova Alice Lacombe Paula Fernandes Lilach Sheiner Alexey Amunts
author_sort	Alexander Mühleip
title	ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
title_short	ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
title_full	ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
title_fullStr	ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
title_full_unstemmed	ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
title_sort	atp synthase hexamer assemblies shape cristae of toxoplasma mitochondria
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/56947c119cc747a6b15d66b6a2139440
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ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria

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