Cervical cancer in the era of precision medicine: A perspective from developing countries

Cervical cancer (CC) constitutes about 70%–80% of squamous cell carcinoma and 10%–15% of adenocarcinoma. In about 90% of CC cases the Human papillomavirus (HPV) infection appears to be the main culprit. Other risk factors include smoking, compromised immune system, birth control pills, starting sex...

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Autores principales:	Naresh Poondla, Dhatri Madduru, Santosh Kumari Duppala, Suresh Velpula, Vandana Nunia, Simmi Kharb, Somenath Ghatak, Ashwani Kumar Mishra, Sugunakar Vuree, Md Kausar Neyaz, Prashanth Suravajhala
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Cervical cancer Prevalence Diagnosis Prevention Treatment Clinical trials Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/56984cbfd9ee4f35990dc0ae6fa62ced
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spelling	oai:doaj.org-article:56984cbfd9ee4f35990dc0ae6fa62ced2021-11-14T04:36:15ZCervical cancer in the era of precision medicine: A perspective from developing countries2667-394010.1016/j.adcanc.2021.100015https://doaj.org/article/56984cbfd9ee4f35990dc0ae6fa62ced2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667394021000150https://doaj.org/toc/2667-3940Cervical cancer (CC) constitutes about 70%–80% of squamous cell carcinoma and 10%–15% of adenocarcinoma. In about 90% of CC cases the Human papillomavirus (HPV) infection appears to be the main culprit. Other risk factors include smoking, compromised immune system, birth control pills, starting sex at a young age, and having many sexual partners. It is also important to note that CC is one among the few completely preventable cancers. It can be reverted or completely cured if detected in early stages or prevented by healthy lifestyle habits, safe sex, regular screening, and vaccination. It is worth mentioning that, with recent advances in medicine, early detection is now possible by affordable, self-sampling and simple procedures and have significantly reduced the mortality rate, however the rate of incidences has not decreased significantly, especially in older women. Commitments and initiatives by governmental and non-governmental entities through screening and vaccinations for CC are nearly reaching to total protection of girls and women. By raising the awareness on early detection and treatment of CC we can not only eliminate cervical cancer but also ensure reproductive health of the women. Hence, the present review is focused to build the awareness regarding CC by presenting an update of the latest medicinal advancements; building the basics of CC such as its causes, types of treatment modalities, advanced treatment modes, opportunities for prevention, latest technology including clinical trials and financial scenario for the treatment of this deadly disease.Naresh PoondlaDhatri MadduruSantosh Kumari DuppalaSuresh VelpulaVandana NuniaSimmi KharbSomenath GhatakAshwani Kumar MishraSugunakar VureeMd Kausar NeyazPrashanth SuravajhalaElsevierarticleCervical cancerPrevalenceDiagnosisPreventionTreatmentClinical trialsNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENAdvances in Cancer Biology - Metastasis, Vol 3, Iss , Pp 100015- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cervical cancer Prevalence Diagnosis Prevention Treatment Clinical trials Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Cervical cancer Prevalence Diagnosis Prevention Treatment Clinical trials Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Naresh Poondla Dhatri Madduru Santosh Kumari Duppala Suresh Velpula Vandana Nunia Simmi Kharb Somenath Ghatak Ashwani Kumar Mishra Sugunakar Vuree Md Kausar Neyaz Prashanth Suravajhala Cervical cancer in the era of precision medicine: A perspective from developing countries
description	Cervical cancer (CC) constitutes about 70%–80% of squamous cell carcinoma and 10%–15% of adenocarcinoma. In about 90% of CC cases the Human papillomavirus (HPV) infection appears to be the main culprit. Other risk factors include smoking, compromised immune system, birth control pills, starting sex at a young age, and having many sexual partners. It is also important to note that CC is one among the few completely preventable cancers. It can be reverted or completely cured if detected in early stages or prevented by healthy lifestyle habits, safe sex, regular screening, and vaccination. It is worth mentioning that, with recent advances in medicine, early detection is now possible by affordable, self-sampling and simple procedures and have significantly reduced the mortality rate, however the rate of incidences has not decreased significantly, especially in older women. Commitments and initiatives by governmental and non-governmental entities through screening and vaccinations for CC are nearly reaching to total protection of girls and women. By raising the awareness on early detection and treatment of CC we can not only eliminate cervical cancer but also ensure reproductive health of the women. Hence, the present review is focused to build the awareness regarding CC by presenting an update of the latest medicinal advancements; building the basics of CC such as its causes, types of treatment modalities, advanced treatment modes, opportunities for prevention, latest technology including clinical trials and financial scenario for the treatment of this deadly disease.
format	article
author	Naresh Poondla Dhatri Madduru Santosh Kumari Duppala Suresh Velpula Vandana Nunia Simmi Kharb Somenath Ghatak Ashwani Kumar Mishra Sugunakar Vuree Md Kausar Neyaz Prashanth Suravajhala
author_facet	Naresh Poondla Dhatri Madduru Santosh Kumari Duppala Suresh Velpula Vandana Nunia Simmi Kharb Somenath Ghatak Ashwani Kumar Mishra Sugunakar Vuree Md Kausar Neyaz Prashanth Suravajhala
author_sort	Naresh Poondla
title	Cervical cancer in the era of precision medicine: A perspective from developing countries
title_short	Cervical cancer in the era of precision medicine: A perspective from developing countries
title_full	Cervical cancer in the era of precision medicine: A perspective from developing countries
title_fullStr	Cervical cancer in the era of precision medicine: A perspective from developing countries
title_full_unstemmed	Cervical cancer in the era of precision medicine: A perspective from developing countries
title_sort	cervical cancer in the era of precision medicine: a perspective from developing countries
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/56984cbfd9ee4f35990dc0ae6fa62ced
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Cervical cancer in the era of precision medicine: A perspective from developing countries

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