A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight

Emerging data indicate that acute kidney injury (AKI) may contribute to a worse prognosis in the infant population. Kidney replacement therapy (KRT) can be used to treat patients with AKI; however, this technique is challenging in patients in the neonatal intensive care units (NICUs) due to the low...

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Autores principales: Chen-Yu Wu, Yung-Chieh Lin, Chih-Chia Chen
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/56998159e89c4901b818e4b40fc84684
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spelling oai:doaj.org-article:56998159e89c4901b818e4b40fc846842021-11-17T06:00:48ZA Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight2296-236010.3389/fped.2021.769220https://doaj.org/article/56998159e89c4901b818e4b40fc846842021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fped.2021.769220/fullhttps://doaj.org/toc/2296-2360Emerging data indicate that acute kidney injury (AKI) may contribute to a worse prognosis in the infant population. Kidney replacement therapy (KRT) can be used to treat patients with AKI; however, this technique is challenging in patients in the neonatal intensive care units (NICUs) due to the low body weights and blood volumes in this population. Peritoneal dialysis (PD) is a potential modality since it is technically less challenging. However, PD has been associated with several disadvantages, including poor fluid status control, catheter-associated leakage, and peritonitis. Unfortunately, these complications can cause the temporary cessation of PD. Continuous kidney replacement therapy (CKRT) may represent a suitable alternative for PD. CKRT may be technically feasible in infants; however, little is known about the application of CKRT in neonates with low body weights. In this report, we discuss three cases of CKRT who were treated in the NICU at a tertiary medical center in southern Taiwan. We selected an adequate catheter diameter and achieved vascular access via an internal jugular vein or umbilical vein. The prescription of an appropriate dose of heparin was then used to prolong the circuit life of the CKRT. The maintenance of circuit durability in neonates with low body weight remains problematic. We hope that our experience can assist with the future clinical management of CKRT in neonates with low body weight.Chen-Yu WuYung-Chieh LinYung-Chieh LinChih-Chia ChenChih-Chia ChenFrontiers Media S.A.articleacute kidney injurydialysislow body weightcontinuous kidney replacement therapy (CKRT)neonatePediatricsRJ1-570ENFrontiers in Pediatrics, Vol 9 (2021)
institution DOAJ
collection DOAJ
language EN
topic acute kidney injury
dialysis
low body weight
continuous kidney replacement therapy (CKRT)
neonate
Pediatrics
RJ1-570
spellingShingle acute kidney injury
dialysis
low body weight
continuous kidney replacement therapy (CKRT)
neonate
Pediatrics
RJ1-570
Chen-Yu Wu
Yung-Chieh Lin
Yung-Chieh Lin
Chih-Chia Chen
Chih-Chia Chen
A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
description Emerging data indicate that acute kidney injury (AKI) may contribute to a worse prognosis in the infant population. Kidney replacement therapy (KRT) can be used to treat patients with AKI; however, this technique is challenging in patients in the neonatal intensive care units (NICUs) due to the low body weights and blood volumes in this population. Peritoneal dialysis (PD) is a potential modality since it is technically less challenging. However, PD has been associated with several disadvantages, including poor fluid status control, catheter-associated leakage, and peritonitis. Unfortunately, these complications can cause the temporary cessation of PD. Continuous kidney replacement therapy (CKRT) may represent a suitable alternative for PD. CKRT may be technically feasible in infants; however, little is known about the application of CKRT in neonates with low body weights. In this report, we discuss three cases of CKRT who were treated in the NICU at a tertiary medical center in southern Taiwan. We selected an adequate catheter diameter and achieved vascular access via an internal jugular vein or umbilical vein. The prescription of an appropriate dose of heparin was then used to prolong the circuit life of the CKRT. The maintenance of circuit durability in neonates with low body weight remains problematic. We hope that our experience can assist with the future clinical management of CKRT in neonates with low body weight.
format article
author Chen-Yu Wu
Yung-Chieh Lin
Yung-Chieh Lin
Chih-Chia Chen
Chih-Chia Chen
author_facet Chen-Yu Wu
Yung-Chieh Lin
Yung-Chieh Lin
Chih-Chia Chen
Chih-Chia Chen
author_sort Chen-Yu Wu
title A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
title_short A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
title_full A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
title_fullStr A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
title_full_unstemmed A Case Series: Continuous Kidney Replacement Therapy in Neonates With Low Body Weight
title_sort case series: continuous kidney replacement therapy in neonates with low body weight
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/56998159e89c4901b818e4b40fc84684
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